43 - Erythema Multiforme Flashcards
EM minor vs major
Minor - skin and lips only
Major - with mucous membrane involvement
Typical vs atypical EM major
Typical - typical targets on the extremities
Atypical - more extensive distribution of atypical, larger targets
Erosions of the eyes and mouth and a transient skin eruption
Fuchs syndrome or
Ectodermosis pluriorificialis or
Mucosal EMM
EM is more prevalent in _____ and has a _____ preponderance
Adolescents and young adults
Male
EM recurrence usually more frequent in _____-associated cases
HSV
Average interval of EM developing after HSV infection
7 days (range, 12-17 days)
Y/N: EM usually follows primary HSV infection.
No - EM usually follows recurrent herpes but may also occur after primary HSV infection.
In most patients, all EM lesions appear within
3 days
EM lesions often first appear (proximally/distally) and then spread in a (centrifugal/centripetal) manner
Distally
Centripetal
EM lesions are usually (symptomatic/asymptomatic)
Asymptomatic
Typical target lesions consist of
- Dusky central disk of blister
- Infiltrated pale ring
- Erythematous halo
Lesions of EM are all _____, in contrast to _____, which are the typical lesions in epidermal necrolysis.
Papules
Macules
Central bulla and a marginal ring of vesicles
Herpes iris of Bateman
Duration of an individual EM lesion is shorter than
2 weeks
Most common cause of EM
HSV (usually HSV-1)
