55 - Mucous Membrane Pemphigoid

Question 1

Most frequent sites of involvement in patients with MMP; often the first and only site affected

Answer 1

Mouth

Question 2

Ocular lesions typically manifest as

Answer 2

Conjunctivitis

Question 3

Early ocular disease is best appreciated by

Answer 3

Slitlamp examination

Question 4

Most frequently affected areas of the skin are the

Answer 4

Scalp, head, neck and upper trunk

Question 5

Predominates in men, lacks mucous membrane involvement, and only in selected cases is associated with IgG autoantibodies against BP23 or BP180

Answer 5

Brunsting-Perry pemphigoid

Question 6

Patients with MMP and IgG autoantibodies directed against _____ was shown to have an increased relative risk for cancer

Answer 6

Laminin-332

Question 7

Most common IgA autoantigen linked to the MMP phenotype is

Answer 7

BP180

Question 8

Blisters of MMP typically develop within the

Answer 8

Lamina lucida

Question 9

Preferred biopsy site for DIF in MMP

Answer 9

Mucous membranes

Question 10

MMP course

Answer 10

Chronic and rarely goes into spontaneous remission

Question 11

Patients with both _____ and _____ anti-basement membrane autoantibodies appear to have a worse prognosis

Answer 11

IgG

IgA