38 - Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease)

Question 1

Subcorneal pustular dermatosis is more common in ______ and in _____

Answer 1

Women

Persons older than 40 years of age

Question 2

Subcorneal pustular dermatosis is frequently associated with various forms of immune dysfunction, most commonly

Answer 2

IgA monoclonal gammopathy

Question 4

Increased serum _____ has been detected in patients with subcorneal pustular dermatosis

Answer 4

IgA

Question 5

Subcorneal pustular dermatosis tend to occur symmetrically affecting mainly

Answer 5

Axillae, groin, abdomen, submammary areas, flexor aspects of the limbs

Question 6

Pus characteristically accumulates in the lower half of the pustule

Answer 6

Hypopyon formation

Question 7

DIF result of subcorneal pustular dermatosis

Answer 7

Usually negative

Question 8

Upon detection of IgA in a pemphigus-like intercellular pattern, patients should be diagnosed as

Answer 8

SPD-type IgA pemphigus

Question 9

Drug of choice for subcorneal pustular dermatosis

Answer 9

Dapsone 50-150 mg daily

Question 10

Y/N: Response of subcorneal pustular dermatosis to dapsone is faster and more dramatic than dermatitis herpetiformis.

Answer 10

No - slower and less dramatic