36 - Sweet Syndrome

Question 1

Sweet syndrome is also known as

Answer 1

Acute febrile neutrophilic dermatosis

Question 2

Types of Sweet syndrome

Answer 2

Classical
Malignancy-associated
Drug-induced

Question 3

Transparent, vesicle-like appearance of the lesions, described as

Answer 3

Illusion of vesiculation

Question 4

Form of skin hypersensitivity occurs when Sweet syndrome skin lesions appear at sites of cutaneous trauma

Answer 4

Cutaneous pathergy

Question 5

Occurrence of a new skin disorder at the site of another unrelated and already healed skin disease

Answer 5

Wolf’s isotopic response

Question 6

Histiocytoid variant often associated with

Answer 6

Malignancy

Question 7

Most patients with giant cellulitis-like variant of Sweet syndrome are

Answer 7

Obese

Question 8

Most common locations of giant cellulitis-like variant of Sweet syndrome

Answer 8

Upper leg

Buttocks

Question 9

Ocular involvement in the ______ forms is uncommon

Answer 9

Malignancy-associated

Drug-induced

Question 10

Mucosal ulcers of the mouth are uncommon in patients with _____ Sweet syndrome

Answer 10

Classical

Question 11

Oral involvement occur more frequently in Sweet syndrome patients with

Answer 11

Hematologic disorders

Question 12

Inflammatory reaction with increased capillary permeability that occurs in up to 25% of patients with acute promyelocytic leukemia treated with all-trans-retinioic acid

Answer 12

Differentiation syndrome

Question 13

Most frequent hematologic dyscrasias associated with leukemia cutis and Sweet syndrome being present in the same skin lesion

Answer 13

Acute myelocytic leukemia

Acute promyelocytic leukemia

Question 14

Conditions associated with classical Sweet syndrome

Answer 14

Infection of upper respiratory and/or GI tract
Inflammatory bowel disease
Pregnancy

Question 15

Classical Sweet syndrome most commonly occurs in

Answer 15

Women

Question 16

Malignancy-associated Sweet syndrome is most often associated with

Answer 16

Acute myelogenous leukemia

Question 17

Most frequently occurring cancers is Sweet syndrome patients with dermatosis-related solid tumors

Answer 17

Carcinomas if the genitourinary organs, breast and gastrointestinal tract

Question 19

Important differentiator between Sweet syndrome and Behcet disease

Answer 19

HLA antigen analysis

B51 - Behcet disease
B54 - Sweet syndrome

Question 20

Therapeutic mainstay for Sweet syndrome

Answer 20

Systemic corticosteroids

Question 21

Other first-line systemic treatments for Sweet syndrome

Answer 21

Potassium iodide

Colchicine

Question 22

Treatment for Sweet syndrome which may result in vasculitis and hypothyroidism

Answer 22

Potassium iodide

Question 25

Drug-induced Sweet syndrome is most commonly associated with

Answer 25

Granulocyte colony-stimulating factor