34 - Granuloma Annulare Flashcards
Granuloma annulare presentation in children and young adults vs adults
Children and young adults - localized annular and subcutaneous form
Adults - generalized or disseminated
Clinical variants of granuloma annulare
Localized Generalized Subcutaneous Perforating Patch
Most common form of granuloma annulare
Localized
Generalized vs localized granuloma annulare
Trunk is frequently involved in the generalized type
Most common site of subcutaneous type of granuloma annulare
Anterior lower legs in a pretibial location
Rare variant of granuloma annulare characterized by transepidermal elimination of necrobiotic collage
Perforating type
Macular lesions that present as erythematous, red brown, or violaceous patches without an annular rim
Patch type
Patch type granuloma annulare reported in
Adult women
Considered a possible triggering factor because if the frequent location of lesions of granuloma annulare on the distal extremities of children
Nonspecific mild trauma
Y/N: Most patients with granuloma annulare do not have diabetes mellitus.
Yes
Link between granuloma annulare and diabetes mellitus is primarily with
Type 1 insulin-dependent diabetes
Association between granuloma annulare and malignancy in adult patients is reported primarily with
Hodgkin and non-Hodgkin lymphoma
Increased prevalence of _____ in generalized granuloma annulare, particular in cases with an annular morphology
Dyslipidemia
Histopathologic findings in granuloma annulare
Foci of inflammation with a central core of altered collagen (necrobiosis) surrounded by a wall of palisaded histiocytes
Prognosis for granuloma annulare
Majority disappear within 2 years