34 - Granuloma Annulare Flashcards

1
Q

Granuloma annulare presentation in children and young adults vs adults

A

Children and young adults - localized annular and subcutaneous form
Adults - generalized or disseminated

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2
Q

Clinical variants of granuloma annulare

A
Localized
Generalized
Subcutaneous
Perforating
Patch
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3
Q

Most common form of granuloma annulare

A

Localized

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4
Q

Generalized vs localized granuloma annulare

A

Trunk is frequently involved in the generalized type

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5
Q

Most common site of subcutaneous type of granuloma annulare

A

Anterior lower legs in a pretibial location

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6
Q

Rare variant of granuloma annulare characterized by transepidermal elimination of necrobiotic collage

A

Perforating type

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7
Q

Macular lesions that present as erythematous, red brown, or violaceous patches without an annular rim

A

Patch type

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8
Q

Patch type granuloma annulare reported in

A

Adult women

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9
Q

Considered a possible triggering factor because if the frequent location of lesions of granuloma annulare on the distal extremities of children

A

Nonspecific mild trauma

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10
Q

Y/N: Most patients with granuloma annulare do not have diabetes mellitus.

A

Yes

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11
Q

Link between granuloma annulare and diabetes mellitus is primarily with

A

Type 1 insulin-dependent diabetes

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12
Q

Association between granuloma annulare and malignancy in adult patients is reported primarily with

A

Hodgkin and non-Hodgkin lymphoma

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13
Q

Increased prevalence of _____ in generalized granuloma annulare, particular in cases with an annular morphology

A

Dyslipidemia

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14
Q

Histopathologic findings in granuloma annulare

A

Foci of inflammation with a central core of altered collagen (necrobiosis) surrounded by a wall of palisaded histiocytes

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15
Q

Prognosis for granuloma annulare

A

Majority disappear within 2 years

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16
Q

Recurrent lesions of granuloma annulare may develop months or even years later, frequently on

A

Same site