7 - INNATE 4

Question 1

which chemokines are produced as a result of PRR signaling

Answer 1

Question 2

which cytokines are produced as a result of PRR signaling

Answer 2

Question 3

what are costimulatory molecules

Answer 3

expression is increased after PRR signaling
B7.1 (CD80), B7.2 (CD86)
these provide signal 2 to T cells in secondary lymphoid tissue

Question 4

how does PRR signaling affect migration

Answer 4

Question 5

cascade of Type I IFN signaling

Answer 5

Question 6

how does PRR signaling affect migration

Answer 6

migration to secondary lymphoid organs

Question 7

chemokine receptors and the result of that

Answer 7

Question 8

what are the inflammatory responses (4 steps)

Answer 8

Question 9

how are monocytes recruited to the site of infection via adhesion molecules

Answer 9

changes the conformation of the adhesion molecule to anchor to the cell next to it

Question 10

what are the different families of adhesion molecules and their relative expression levels

Answer 10

families:
selecting
integrins
immunoglobulin superfamily

some are expressed at baseline while others are expressed when there is an infection

Question 11

how do leukocytes roll along the vascular endothelium

Answer 11

Question 12

which leukocytes are recruited to the site of infection

Answer 12

monocytes (precursors of macrophages) neutrophils and other leukocytes

Question 13

what are the steps of migration

Answer 13