29 - B CELLS 3

Question 1

what is the general structure of an antibody (immunoglobulin)

Answer 1

Question 2

where are the variable and constant region on an antibody

Answer 2

Question 3

what is the function of the variable regions

Answer 3

Question 4

what is the function of the constant regions

Answer 4

Question 5

what are the fragments of an antibody

Answer 5

Question 6

what is the 3D structure of an antibody

Answer 6

Question 7

what is the complementarity determining region (CDR) on the variable region

Answer 7

antigen binding site (direct contact with Ag)
hypervariable loops:
3 loops per variable domain
not part of the beta strands
CDRs have the greatest variability in the antibody sequence
they are at the extremities of the antibody

Question 8

what type of bonding does Ag binding involve

Answer 8

Question 9

what are the major classes of antibody

Answer 9

there are 5 (MEGA D)
IgM
IgD
IgG
IgE
IgA

Question 10

how are the classes of antibodies differentiated

Answer 10

Question 11

characteristics of IgM

Answer 11

Question 12

characteristics of IgD

Answer 12

Question 13

characteristics of IgG

Answer 13

Question 14

characteristics of IgE

Answer 14

Question 15

characteristics of IgA

Answer 15

Question 16

summary

Answer 16