35 - B CELLS 9 Flashcards
what does tolerance ensure
where do T cells develop
thymus key anatomy and cell types
as what kind of cells do T cell precursors enter the thymus and then what happens
what process do T cells go through to ensure self-tolerance
how does positive selection work
what is AIRE and what does it do in negative selection
how does negative selection work
what is peripheral tolerance
summary
where and how do B cells develop?
how does negative selection of B cells in bone marrow happen (central tolerance)
B cell maturation
receptor editing of potentially autoreactive receptors
combinatorial diversity as well as junctional diversity can be involved in the self reactive BCRs
summary of B cell development
B and T cell development compare and contrast
reminder of what a properly functioning immune system is
what happens when proper immune system breaks down
what are some mechanisms of tolerance
what are the different types of autoimmunities
summary of tolerance
