11 - LINKING 2 Flashcards
location of DC vs T cell activation
DC: at site of infection
T cells: in lymph nodes
by which adhesions molecules do T cells enter the lymph nodes
first selectins and then integrins and then diapedesis
what do selectins do to the T cells
sequential steps of T cell entry into lymph nodes
what is antigen sampling once in lymph node
what happens after the T cell encounters its Ag
what is the timing of T cell activation
T cell characteristics
what are CD8+ T cells
become effector cytotoxic T lymphocytes (CTLs) once activated
cannot be any other type of T cell after activation
produces a distinct cytokine profile and regulates distinct activities in the body
what are CD4+ T cells
produces a distinct cytokine profile and regulates distinct activities in the body
diagram of activation of CD8+ T cells
diagram of activation of CD4+ T cells
how do PAMPs influence the type of effector T cell that is going to arise upon activation