34 - B CELLS 8 Flashcards
what are some key antibody functions
characteristics of FcR (Rc Receptors)
receptors are what help Igs opsonize, act on cells and get across cells
Rc receptor specificity
what are the functions of Fc receptors
reminder of the definition of opsonization
promotes and/or enhances the engulfment of antigens by phagocytes
what allows for crosslinking of Fc receptors?
what is the effector function of IgG
what is antibody dependent cell mediated cytotoxicity (ADCC)
activates the killing activity of several types of cytotoxic cells, for example NK cells
how does ADCC work for NK cells
Fc receptors and granulocytes
antibody dependent degranulation from granulocytes
what are the effector functions of IgE
Th2 response and degranulation
what is neutralization
protects against viral or bacteria infections, or against the damaging effects of toxins
characteristics of neutralization
how are toxins neutralized?
how are bacteria neutralized
how are viruses neutralized
reminder of what complement activation leads to
generation of the membrane attack complex (MAC), inflammation and/or opsonization
blast from the past of the classical pathway
antibodies and the complement system
where are different Ig classes found in different parts of the body
what are the effector functions of IgD
summary
