23 - T CELLS 5 Flashcards
what is signal 3, effector cytokine and master transcriptional regulatory for Th17 cells
what are the functions of Th17 cells
Th17 cells and inflammation
what response is the Th17 response to infection
type 3 response
what are the different effector functions of Th17 cells
production of antimicrobial peptides
increase epithelial cell turnover
induce other cells to produce G-CSF
induce other cells to secrete chemokines
attract more Th17 cells
how do Th17 effector cells induce production of antimicrobial peptides
how do Th17 effector cells increase epithelial turnover
how do Th17 effector cells induce other cells to produce G-CSF
how do Th17 effector cells induce other cells to secrete chemokines
how do Th17 effector cells recruit additional Th17 cells
secrete CCL20
other pro-inflammatory effects of Th17 cells
leads to the acute phase response
what is psoriasis
what is a monoclonal antibody
what are the two approaches to targeting IL-17 in psoriasis
reminder of ILCs and two examples
signal 3, effector cytokines and master transcriptional regulator of Tfh cells
IL-21 helps the proliferation of B cells
the type of pathogen determines with type 1/2/3 effector cytokine is released
Tfh signaling
STAT3 is also phosphorylated for Th 17 cells
but, the area in which this protein is phosphorylated is different
IL-21 is in high amounts regardless, and the rest is decided by the type of infection
what do Tfh secreted cytokines do
signal activates B cells to produce specific types of antibodies
Tfh cells interact directly with B cells
this is in response to all types of pathogens!
preview of B cell module and take home message
summary
characteristics of NKT cells and their similarities to NK vs T cells
quiz question
