69 - Relapsing Polychondritis

Question 1

Most frequence occurrence in relapsing polychondritis

Answer 1

Auricular chondritis

Question 2

Most common manifestations of ocular inflammation

Answer 2

Episcleritis

Scleritis

Question 3

T cells in RP are primarily

Answer 3

CD4

Question 4

DIF inconsitently shows

Answer 4

Immunoglobulins and C3 at the junction perichondrium cartilage

Question 5

The role of the humoral response was bases on the presence of antibodies to _____ in a third of patients with RP

Answer 5

Collagen II

Question 6

RP is likely a _____-mediated disease as serum levels of interferon-gamma, IL-12 and IL-2 parallel changes in disease activity, while the levels of _____ cytokines do not

Answer 6

T-helper-1

T-helper-2

Question 7

3 clinical phenotypes of RP

Answer 7

Hematologic
Respiratory
Mild

Question 8

First group of patient with myelodysplasia was associated with

Answer 8

Death

Question 9

Second group of patients with tracheobronchial involvement was associated with

Answer 9

Infections

Question 10

Most frequently used biologic in RP with variable results

Answer 10

Infliximab