28 - Psoriasis Flashcards
Types of psoriasis based on age of onset
Type I - onset before 40 years and HLA associated
Type II - age after 40 years
Also known as isomorphic response
Koebner phenomenon
Koebner reaction usually occurs
7-14 days after injury
Psoriasis vulgaris is seen approximately in _____% of patients
90
Type of psoriasis: lesions may extend laterally and become circinate because of the confluence of several plaques
Psoriasis gyrata
Type of psoriasis: partial central clearing resulting in ringlike lesions
Annular psoriasis
Type of psoriasis: usually associated with lesional clearing and portends a good prognosis
Annular psoriasis
Type of psoriasis: lesions in the shape of a cone or limpet
Rupioid psoriasis
Type of psoriasis: ringlike, hyperkeratotic concave lesion, resembling an oyster shell
Ostraceous psoriasis
Type of psoriasis: thickly scaling, large plaques, usually on the lower extremities
Elephantine psoriasis
Hypopigmented ring surrounding individual psoriatic lesions usually associated with treatment, most commonly UV radiation or topical steroids
Woronoff ring
Pathogenesis of Woronoff ring
Not well understood but may result from inhibition of prostaglandin synthesis
Guttate psoriasis has the strongest association to
HLA-Cw6
Frequently precedes or is concomitant with the onset or flare of guttate psoraisis
Streptococcal throat infection
Common adult presentation of psoriasis in Korea and other Asian countries
Small plaque psoriasis
Characterized by fever that lasts several days and a sudden generalized eruption of sterile pustules; waves of fever and pustules
Generalized pustular psoriasis (von Zumbusch)
Tends to occur after a viral infection and consists of widespread pustules with generalized plaque psoriasis
Exanthematic pustular psoriasis
Exanthematic pustular psoriasis vs von Zumbusch
Exanthematic pustular psoriasis - no constitutional symptoms and tends not to recur
Characterized by pustules on a ringlike erythema that sometimes resembles erythema annulare centrifugum
Annular pustular psoriasis
Variant of pustular psoriasis occuring in pregnancy
Impetigo herpetiformis
Impetigo herpetiformis onset
Early in the third trimester and persists until delivery
Y/N: Impetigo herpetiformis tends to develop earlier in subsequent pregnancies.
Yes
Impetigo herpetiformis is often associated with
Hypocalcemia
Rare variant of pustular psoriasis that is localized to the palms and soles
Palmoplantar pustular psoriasis or
Pustulosis palmaris et plantaris
Palmoplantar pustular psoriasis vs palmoplantar pustulosis
Palmoplantar pustular psoriasis - chronic plaque psoriasis is present
Y/N: Pustulosis palmaris et plantaris has a sex predilection
Yes - more common in females
Strongly associated with pustulosis palmaris et plantaris
Smoking
Also knows as dermatitis repens
Acrodermatitis continua of Hallopeau
Napkin psoriasis usually between the ages of
3 and 6 months
Napkin psoriasis prognosis
Disappear after the age of 1 year
May be an underlying nevus, possibly an inflammatory linear verrucous epidermal nevus
Linear psoriasis
Nail changes are found in up to _____% of patients
40
Nail finding that is considered to be nearly specific for psoriasis
Oil spotting
Nail segment involved: pitting
Proximal matrix
Nail segment involved: onychorrhexis
Proximal matrix
Nail segment involved: Beau’s lines
Proximal matrix
Nail segment involved: leukonychia
Intermediate matrix
Nail segment involved: focal onycholisis
Distal matrix
Nail segment involved: thinned nail plate
Distal matrix
Nail segment involved: erythema of the lunula
Distal matrix
Nail segment involved: “oil drop” sign or “salmon patch”
Nail bed
Nail segment involved: onycholysis
Nail bed
Hyponychium
Nail segment involved: subungual hyperkeratosis
Nail bed
Hyponychium
Nail segment involved: crumbling and destruction plus other changes secondary to the specific site
Nail plate
Nail segment involved: cutaneous psoriasis
Proximal and lateral nail folds
Y/N: Alopecia is a common observation is scalp psoriasis
No - not a common observation
Present as asymptomatic erythematous patches with serpiginous borders; idiopathic inflammatory disorder resulting in the local loss of filiform papillae
Geographic tongue or
Benign migratory glossitis or
Glossitis areata migrans