2 - Pathology of Skin Lesions

Question 1

Number of reactive units

Answer 1

4

Question 2

Reactive units of the skin

Answer 2

1 Superficial reactive unit
2 Dermal reactive unit
3 Subcutaneous reactive unit
4 Appendages

Question 3

Cells that form bulk of the epidermis

Answer 3

Keratinocytes

Question 4

Stain: elastic fiber

Answer 4

Verhoeff-Van Gieson (black)

Question 5

Stain: mucin, mast cell

Answer 5

Toluidine blue (mucin: blue, mast cell granules: metachromatic)

Question 6

Stain: collagen, smooth muscle

Answer 6

Masson’s trichrome (collagen: blue-green, smooth muscle: red)

Question 7

Stain: mast cell cytoplasm

Answer 7

Leder stain (red)

Question 8

Stain: glycogen, fungi

Answer 8

Periodic acid-Schiff (glycogen: red, fungi: red)

Question 9

Stain: acid mucopolysaccharides, such as mucin

Answer 9

Alcian blue (blue)
Colloidal iron (blue)
Mucicarmine (pink/red)

Question 10

Stain: amyloid

Answer 10

Congo red (red)
Thioflavin T (yellow/yellow-green)
Crystal violet (red-purple metachromatically)

Question 11

Stain: iron

Answer 11

Prussian blue/Perls stain (deep blue)

Question 12

Stain: melanin

Answer 12

Fontana-Masson (black)

Question 13

Stain: calcium

Answer 13

Von Kossa (black)
Alizarin red (orange-red)

Question 14

Stain: lipids

Answer 14

Oil red O (red)
Sudan black (black)

Question 15

Stain: fungus

Answer 15

Gomori methenamine silver (gray-black)

Periodic acid-Schiff (red)

Question 16

Stain: mycobacteria

Answer 16

Ziehl-Neelsen; Fite acid-fast stain (red)

Auramine-rhodamine (red-yellow)

Question 17

Stain: spirochetes

Answer 17

Warthin-starry (black)

Question 18

Stain: myeloid cells, mast cells, Leishmania, Histoplasma

Answer 18

Giemsa (myeloid cells: blue, mast cells: blue)

Question 19

Split: granular layer (3)

Answer 19

Pemphigus foliaceus
Subcorneal pustular dermatosis
Staphylococcal scalded skin syndrome/bullous impetigo

Question 20

Split: spinous layer (4)

Answer 20

Spongiotic dermatitis
Herpes virus infection
Friction blister
Familial benign pemphigus

Question 21

Split: suprabasal (2)

Answer 21

Pemphigus vulgaris

Darier disease

Question 22

Split: subepidermal (5)

Answer 22

Epidermolysis bullosa
Epidermolysis bullosa acquisita
Bullous pemphigoid
Dermatitis herpetiformis
Porphyria cutanea tarda

Question 23

Junctional blistering (2)

Answer 23

Bullous pemphigoid

Junctional epidermolysis bullosa