26 - Seborrheic Dermatitis Flashcards
Seborrheic dermatitis usually appears in
Adolescents and young adults
Peak incidence of infantile seborrheic dermatitis
3 months
Seborrheic dermatitis has a (male/female) preponderance
Male
Y/N: Seborrheic dermatitis is often influenced by a seasonal impact.
Yes
Seborrheic dermatitis becomes more common and severe in
Cold and dry climates
Prognosis of infantile seborrheic dermatitis
Normally resolves spontaneously within the first 6-12 months of life
Characterized by desquamative erythroderma, sparse hair, frequent loose stools and failure to thrive
Leiner disease
Leiner disease is associated with congenital or acquired deficiencies of
C3, C5
Asbestos-like scalp
Pityriasis amiantacea
Pityriasis amiantacea is more common in (males/females)
Females
Y/N: Alopecia is a common feature of pityriasis amiantacea.
Yes
Most frequent skin conditions associated with pityriasis amiantacea
Psoriasis (35%)
Eczematous conditions like SD and AD (34%)
A _____ form of Malassezia, a pathogenic form observed in pityriasis versicolor, has not been detected in SD.
Mycelial
Most important Malassezia species identified in SD
M. globosa
M. restricta
Agonists to aryl hydrocarbon receptor, which is involved in the differentiations of Th 17 cells and the mediation of contact sensitivity
Malassezin
Could explain the lack of a positive correlation between the number of Malassezia and the severity of dandruff
Host susceptibility factor
SD expressed in Parkinson disease has been thought to result from
Elevated levels of sebum allowing the proliferation of Malassezia
SD-like dermatitis also appears in patients with _____ or _____ deficiency
Zinc
Biotin
Scalp dermoscopy of psoriasis vs SD
Psoriasis: twisted loop, red dots and globules, glomerular vesses
SD: arborizing vessels, atypical red vessels
Diagnostic criteria suggested by Beare and Rook for infantile seborrheic dermatitis
Early onset (before 6 months of age)
Erythematous and scaling rash distributed in the scalp, diaper, or flexural areas
Relative absence of pruritus
Has generally more purpuric lesions and tends to desquamate on the scalp and ulcerate on the folds and mucosal areas
Langerhans cell histiocytosis, previously called Letterer-Siwe disease
Dandruff aka
Pityriasis simplex capillitii