4.1 - CVP - PPT CVP DDx (Cardiovascular Section) Flashcards
Week 4, Monday
Describe the pH scale (neutral vs acidic vs alkaline)
Neutral = 7
Acidic <7
Alkaline >7
Describe the abnormal responses to exercise
Angina
Dyspnea
Pallor
Cyanosis
Dizziness, light-headedness
Ataxia
Intermittent claudication
Blunted BP response
Hypertensive BP response >200/110 mmHg
Drop in SBP >10-15 mmHg
Significant change in EKG rhythm
What is angina?
Substernal (chest) symptoms - heaviness, pressure, tightness, burning, squeezing, choking
Includes radiation to (L) neck, arms, back, or epigastrum
Describe the 3 types of angina - stable, unstable, Prinzmetal
Unstable - new, recent onset (within 6 wks); occurs at rest w/o precipitating factors; or abrupt change in patient’s pattern of symptoms
Stable - experienced at predictable myocardial workloads / demands / effort; “stable pattern”
Prinzmetal - coronary artery vasospasm
Describe the clinical implications of unstable vs stable angina
Stable - want to stay under the anginal threshold while exercising; may use ntg prn if angina is present or prophylactic medications (long-acting nitrates, beta-blockers, calcium channel blockers) to decrease likelihood of experiencing angina
Unstable - usually signifies worsening of the underlying CAD
What is nitroglycerin used for?
Describe how ntg should be used/
Taken prn during angina
Sublingual dose
Have patient lay down as expecting BP to drop
Releases NO, which is a potent vasodilator -> increased BF to heart, decreased TPR
Should act to relieve pain w/in 1-2 min
If no relief after 2 or 3 doses or within 20 min -> call 911
Describe the appropriate management for unstable vs stable angina
Stable - stay below anginal threshold during exercise
Unstable - immediate medical evaluation; i.e., call 911; goal is to prevent MI!
Describe the clinical presentation of Prinzmetal angina
NOT preceded by increased myocardial demands
More common in women <50 yrs
S/sx:
- Pain often occurs early in AM, awakening patients from sleep
- Occurs at rest
- Sx difficult to induce w/ exercise
Describe the medical management of Prinzmetal angina
Nitrates (ntg)
CCBs
What is a myocardial infarction?
Cell death of the myocardium
What physiologically causes an MI?
Lack of blood supply to myocardium –> tissue injury & infarction
Often results from plaque rupture with thrombus formation in a coronary vessel
What life-threatening condition can an MI lead to?
Cardiogenic shock
- Insufficient BP to heart & vital organs
What cardiac enzymes are present and indicative of an MI? Describe these
Creatine-kinase-myocardial band (CK-MB)
Lactic dehydrogenase (LDH)
Troponin
Myoglobin
Cell death -> elevation in enzymes (does not occur w/ just ischemia)
Diagnosis of MI:
- Serial measurement troponin, AND
- Clinical changes
Describe the clinical presentation of an MI
Chest pressure
Radiating pain to L arm, jaw, and thorax
Dizziness, light-headedness
Diaphoresis
Fatigue, weakness
Women:
Mental status changes
Dyspnea
Weakness / lethargy
GERD pain
Anxiety / depression
Sensation of inhaling “cold air”
Achiness, heaviness, weakness of BIL UEs
Symptoms relieved by antacids
When is it okay to initiate PT following an MI?
When cardiac troponin starts falling (before this, the cells are still dying)