2nd Page Flashcards
What is immunity?
The sum total of the defense mechanisms of the human body to resist infectious disease.
What are the two main types of immunity?
Innate and Adaptive
What is INNate Immunity?
Natural, Non-specific immunity.
What is Adaptive Immunity?
Acquired, specific immunity.
What are the 1st line of defense?
External - physical and biochemical
What are the 2nd line of defense?
Internal - cellular and fluid components
What is Cellular Immunity?
Involves active Ag and passive Ab
What is Humoral Immunity?
Involves active Ag and passive Ab
What are the 3rd line of defense?
Cellular Immunity and Humoral Immunity
It is TLRs (toll-like receptors) (Immunity)
Natural
Protection by natural means without antibody production (Immunity)
Natural
Present at birth (Immunity)
Natural
Have uniform response (Immunity)
Natural
Lacks memory (Immunity)
Natural
Rapid/ Immediate (Immunity)
Natural
Have specific T and B cells (Immunity)
Acquired
Have short duration (Immunity)
Natural
Involves antibody production (Immunity)
Acquired
Diverse response (Immunity)
Acquired
Not present at birth (Immunity)
Acquired
With memory (Immunity)
Acquired
Long duration (Immunity)
Acquired
What are under physical barriers?
intact skin
mucuous membrane
cilia
cough reflux
What are under biochemical secretions?
lysozyme
lactic acid
sebum
earwax
What are under cellular components in 2nd line?
phagocytic cells
eosinophils
basophils and mast cells
APCs
NK cells
What are under humoral components in 2nd line?
Complement
Cytokines
Lysozymes
Properdin
Betalysin
What are under cellular components in 3rd line?
Specialized lymphocytes
T cells
B cells
Plasma cells
APCs
What are under humoral components in 3rd line?
ACC
Antibodies
Cytokines
Complement
What is the substance introduced in active immunity?
AG
Antigen
What is the substance introduced in passive immunity?
PB
Antibody
What is Ab production in ACTIVE immunity?
Done by the body
What is Ab production in PASSIVE immunity?
Not done by the body
What is the duration of immunity in Active Immunity?
Long term
What is the duration of immunity in Passive Immunity?
Short term
What is immunity response in Active Immunity?
Slow
What is immunity response in Passive Immunity?
Rapid I Immediate
What are examples of artificial active immunity?
- Vaccination for smallpox
- BCG for Mycobacterium bovis
- Cholera vaccine
- Toxoid for Clostridium tetani
- Polio
What are examples of natural active immunity?
Actual infection
What are examples of natural passive immunity?
- Pregnancy
- Colostrum (rich in IgA)
What are examples of artificial passive immunity?
- Anti-rabies serum
- Rhogam
- HBIG (Human HBIG to prevent hepatitis B in those not actively immunized with the HepB vaccine)
The process by which powder form of smallpox scabs or lesions was inhaled by affected individuals to produce protection against smallpox
Variolation
The process by which a material from cowpox lesions was injected into individuals with smallpox to develop immunity against it
Vaccination
The process by which a less infectious form of an agent is produced through heat, aging, or chemical means
Attenuation
The phenomenon in which exposure to one agent produces protection against another agent
Cross-immunity