15e. Urinary Health - UTIs Flashcards

1
Q

What is an infection in the kidney called?

A

Pyelonephritis

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2
Q

What is an infection in the bladder called?

A

Cystitis

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3
Q

What is an infection in the urethra called?

A

Urethritis

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4
Q

Disturbance to what can result in infection?

A

Microbial terrain

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5
Q

Which bacteria relates to 80-90% of UTIs?

A

Escherichia coli
(E. coli)

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6
Q

Signs and symptoms of cystitis

A

Dysuria
Frequent/urgent urination
Suprapubic pain
Foul smelling/cloudy urine
Haematuria

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7
Q

Signs and symptoms of urethritis

A

Dysuria
Urethral discharge
Pruritis

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8
Q

Signs and symptoms of pyelonephritis

A

Fever
Chills
Nausea
Loin discomfort
Blood or pus in urine
(red flag!)

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9
Q

Causes and risk factors for UTIs

A

Women
Menopause
Pregnancy
Sexual activity
Elderly
BPH
Antibiotics
Intestinal dysbiosis
Gut-vagina-bladder axis

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10
Q

Why are women more at risk of getting a UTI?

A

Shorter urethra
More chance of bacteria ascending to bladder

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11
Q

Why is menopause a risk factor for getting a UTI?

A

Low oestrogen reduces vaginal mucus
Reduces monitoring of bacterial species

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12
Q

Why is pregnancy a risk factor for getting a UTI?

A

Pressure of growing uterus on ureter and bladder preventing complete voiding

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13
Q

Why is sexual activity a risk factor for getting a UTI?

A

Introduces new bacteria

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14
Q

Why is being elderly a risk factor for getting a UTI?

A

Lowered immunity
Decreased mobility
Reduced mucin
Reduced bacterial adherence

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15
Q

Why is BPH a risk factor for getting a UTI?

A

Can obstruct urine flow causing bladder urinary stasis

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16
Q

Why are antibiotics a risk factor for getting a UTI?

A

Increases likelihood of opportunistic bacteria proliferating

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17
Q

Why is intestinal dysbiosis a risk factor for getting a UTI?

A

Bacteria can translocate from the perianal region and descend to the genitourinary tract

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18
Q

What happens in the gut-vagina-bladder axis?

A

Bacterial vaginosis increases UTI risk
G. vaginalis can ascend into the urinary tract, damage bladder lining and reactivate latent E. coli

19
Q

What should be avoided/reduced to support a UTI?

A

Simple sugars/refined carbs
Caffeine/diet soft drinks/alcohol
Red meat/pork/poultry

20
Q

Why should simple sugars/refined carbs be reduced/avoided in a UTI?

A

Negatively impact the microbiome
Increase inflammation
Compromise immunity

21
Q

Why should caffeine, diet soft drinks and alcohol be reduced/avoided in a UTI?

A

They can irritate the urinary tract
Caffeine - increases detrusor muscle contraction, contributing to urinary frequency and urgency

22
Q

Why should red meat, pork and poultry be avoided in a UTI?

A

Can act as a reservoir for uropathogenic E. coli
Promote inflammation (arachidonic acid)

23
Q

What should the natural approach to a UTI include?

A

Naturopathic diet
Pre-/probiotic foods
Hydration
Cranberry

24
Q

Why is the naturopathic diet good for supporting UTIs?

A

Plant-based diets are associated with reduced incidence of UTIs
Phytonutrients are antimicrobial, AO and anti-inflammatory
High fibre may modulate microbiota and prevent E. coli growth

25
Why are pre-/probiotic foods good for supporting UTIs?
To optimise microbiota colonisation
26
Why is hydration good for supporting UTIs?
Flush out bacteria through the urinary tract
27
Why is cranberry good for supporting UTIs?
Proanthocyanins reduce bacterial adhesion to bladder endothelium
28
Dosage of cranberry to support UTIs
15-30ml unsweetened/undiluted juice/day 500mg powder 3/day
29
Supplements to support UTIs
D-mannose A C D Zn Probiotic
30
Why is D-mannose good for supporting UTIs?
Creates a coating around E. coli that prevents its binding to urothelium
31
Dosage of D-mannose to support UTIs
500mg every 2hr for 3-5 days
32
Why is vit A good for supporting UTIs?
Maintains integrity of urinary tract mucus membrane Supports lymphatic tissues/immune cells
33
Dosage of vit A to support UTIs
5000iu/day
34
Why is vit C good for supporting UTIs?
Regulates lymphocytes/phagocytes/NKCs Helps maintain integrity of uroepithelial lining
35
Dosage of vit C to support UTIs
500-5000mg/day (divided doses)
36
Why is vit D good for supporting UTIs?
Promotes production of anti-microbial substances Strengthens innate mucosal immunity
37
Why is Zn good for supporting UTIs?
Increases resistance to infection
38
Dosage of Zn to support UTIs
15mg - prevent Up to 60mg - during acute infection
39
Which probiotic is good for supporting UTIs?
Lactobacillus
40
Herbal support for UTIs
Crataeva Bearberry Cornsilk
41
Why is crataeva good for supporting UTIs?
Helps flush urinary tract
42
Why is bearberry good for supporting UTIs?
Anti-inflammatory Urinary antiseptic
43
Why is cornsilk good for supporting UTIs?
Mild diuretic Demulucent