11.1b Pregestational Diabetes Flashcards
1
Q
Vascular Diseases of Diabetes
A
- Retinopathy
- Nephropathy
2
Q
Pregestational Diabetes
A
- Almost always insulin dependent
- First trimester - Glucose is usually lower and insulin response to glucose is enhanced
- Insulin needs steadily increase after 1st trimester
- Insulin resistance begins 14-16 weeks gestation
- Preconception counseling recommended for all women with diabetes
3
Q
Risks of Pregestational Diabetes
A
- Risk of miscarriage is high if diabetes is present early in pregnancy or close to contraception
WITHOUT VASCULAR DISEASE
- Risk of fetal macrosomia (birthweight greater than 4000-4500g or 90%)
- Disproportionate increase in shoulder, trunk and chest size
- Increase likelihood of c-section due to failure of fetal descent
- Episiotomy, forceps and vacuum birth also more likely
MEDICAL COMPLICATIONS
- Hypertension
- Preeclampsia
- C-section
- Preterm Birth
- Maternal mortality
- RISKS INCREASE WITH DURATION AND SEVERITY
4
Q
Hydramnios
A
- Diabetes increases risk of this in 3rd trimester
RISKS
- Placental abruption
- Uterine dysfunction
- Postpartum Hemorrhage
- Vaginal Infection
- UTI
5
Q
Ketoacidosis
A
- Occurs most often in 2nd and 3rd trimester
- Can occur in glucose levels barely above 200
- Infection/Illness/Stress increases hepatic glucose production and decreased peripheral uptake of glucose leading to hyperglycemia
- Ketoacidosis can lead to intrauterine fetal death
6
Q
Hypoglycemia
A
- Risks highest early in pregnancy when hepatic glucose production is low and peripheral uptake of glucose is high
7
Q
Euglycemia
A
- Normal glucose
8
Q
Hyperglycemia Risks
A
- Miscarriage
- Congenital malformations
- Respiratory distress syndrome
- Extreme prematurity
9
Q
IUDF (Stillbirth) Causes
A
- Diabetes
- Placental insufficiency
- Fetal Growth Restriction
- Macrosomia
- Polyhydramnios
- Obstructed Labor (Intrapartum Stillbirth)
10
Q
Hyperglycemia Anomalies
A
- Happen in first trimester due to organs forming during this time
- Main birth defect of birth diabetes
- Most effected systems are CVD and CNS
11
Q
Fetus
A
- Fetal pancreas releases insulin at 10-14 weeks gestation
- Insulin acts as a growth hormone so when baby releases extra insulin (hyperinsulinism) due to increased mom blood glucose, it increases fetal size (macrosomia)
12
Q
Macrosomia Risks
A
- Brachial Plexus Palsy
- Facial Nerve Injury
- Humerus/Clavicle Fracture
- Cephalhematoma
13
Q
Care Management
A
- Baseline renal function (24 hour urine collection) to measure protein and creatinine
- Urinalysis and culture to assess UTI
- Thyroid function tests due to risk of coexisting thyroid issues
- A1C Levels (Less than 6.5 is perfect)
14
Q
Education
A
- Management and potential effects
- Insulin administration
- Hypo/Hyperglycemia
- Diabetic Diet
15
Q
Associated Fetal Injuries
A
- Disruption of oxygen transfer
- Birth trauma