10 JUNE 2019

Question 1

when is GABA fast acting?

Answer 1

w/ a GABA a receptor

Question 2

when is GABA slow acting?

Answer 2

w/ a GABA b receptor

Question 3

what type of response is a GABA amino acid?

Answer 3

inhibitory : generates an IPSP response

Question 4

what is the most prevalant inhibitory fast-acting amino acid?

Answer 4

GABA

Question 5

what is the most prevalent excitory fast-acting amino acid?

Answer 5

Glutamate

Question 6

when is gluatmate fast acting?

Answer 6

w/ AMPA receptor

Question 7

when is glutamate slow acting?

Answer 7

w/ NMPA receptor

Question 8

what type of response does glutamate do?

Answer 8

excitory: EPSP repsonse

Question 9

what two things can serotonin affect?

Answer 9

changes our perceptio of pain

and adjust our arousal levels

Question 10

what pathology does serontonin affect?

Answer 10

depression - most common anti-depressent drug

Question 11

what type of fast slow methods does the CNS and PNS have?

Answer 11

CNS has BOTH fast/slow = gas pedal + breaks
PNS has ONLY fast = gas pedal
- to slow you dont press the gas

Question 12

dopamine affects what four things?

Answer 12

motor activity
cognition
behavior
pleasure

Question 13

dopamine is associated with what?

Answer 13

addiction

Question 14

norepinephrine is part of what system?

Answer 14

fight or flight which is the

autonomic - sympathetic system

Question 15

tell me two things about norepinephrine:

Answer 15

increases attention to sensory information

apart of autonomic - sympathetic system

Question 16

what does neuroplasticity mean?

Answer 16

the brain can adjust : so it can increase in ability or decrease in ability but there is the ability to change

Question 17

what are the three big amino acids we need to know?

Answer 17

Acetylcholine
gluatmate
GABA

Question 18

how many other random proteins do we need to know?

Answer 18

five

Question 19

what are the five random proteins we need to know?

Answer 19

histamine 
epinephrine 
dopamine 
serotonin 
peptide

Question 20

tell me two things about histamine:

Answer 20

it can create an interaction affect

and is part of the neuro inflammatory response

Question 21

norepinephrine increase what?

Answer 21

attention to sensory information

Question 22

amines are what?

Answer 22

slow acting neurotransmitters

Question 23

what are the two types of peptides?

Answer 23

• endogenous opioids

- substance P

Question 24

endogenous opioids do what?

Answer 24

inhibit perception of pain

Question 25

substance p can be

Answer 25

a neurotransmitter or modulator

Question 26

substance p are?

Answer 26

pain pathways

Question 27

habituation def:

Answer 27

decrease response from a repeated begin stimulus

Question 28

a short term habituation occur where?

Answer 28

presynaptic facilitation

Question 29

what two ways can you get a presynaptic facilitation habituation:

Answer 29

1- more presynaptic inhibition | 2 - less presynaptic facilitation

Question 30

name two examples of "pathologies" w/ habituation:

Answer 30

tactile defensiveness | vestibular disorders

Question 31

a long term habituation occurs where :

Answer 31

post synpatic membrane

Question 32

how do you get a long term habituation:

Answer 32

you take away the receptors on the membrane so there can no longer be a facilitation response: down regulates

Question 33

down regulate def:

Answer 33

less receptitive to AP

Question 34

how do you down regulate

Answer 34

you INTERALIZE or pull down membrane receptors from the post synaptic terminal making htem INACTIVE = flipping the switch permenantly so the lights are off

Question 35

when you down regulate what happens to potential

Answer 35

it reduces the chance of AP

Question 36

up regulate def:

Answer 36

increase recepitiveness to neurotransmitters

Question 37

how do you up regulate?

Answer 37

take receptors inside the cell & stick it up in the membrane = EXTERNALIZE = ACTIVE = unlock the gate to allow ion to flow in

Question 38

when you up regulate what happens to potential?

Answer 38

increases the chance of an AP

Question 39

what does myasthentic gravis mean?

Answer 39

muscles dont work BIG time

Question 40

what are three bad things that happen with MG?

Answer 40

1. membrane unfolds 2. receptors move closer to the surface 3. the amount of acteylchloline receptors decrease

Question 41

what are the consequences of the bad things in the MG?

Answer 41

the acteylchloline can't be recycled so the left over proteins gets gobbled up by closer those receptors closer to the surface

Question 42

what three things do we need to know for neuroplasticity?

Answer 42

1 - habituation 2- experience-dependent plasticity 3 - recovery or maladaptive behavior

Question 43

what does LTP (long term potentiation do)

Answer 43

converts a silent synapse to an active synapse