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Microbiology > Yersinia and other notifiable agents > Flashcards

Yersinia and other notifiable agents Flashcards

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Biology 101 flashcards
1
Q

Where is Yersinia pestis endemic?

A

south western US

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2
Q

How is Yersinia pestis transmitted?

A

flea bite and contact with infected carcass

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3
Q

what are the reservoirs for Yersinia pestis?

A

rodents

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4
Q

what are the clinical manifestations of the bubonic form of Yersinia pestis?

A

fever, lethargy, enlarged LNs

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5
Q

what are the clinical manifestations of the pneumonic form of Yersinia pestis?

A

respiratory signs +/- septicemia

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6
Q

what are the clinical manifestations of the septic form of Yersinia pestis?

A

no lymphadenopathy, fever, lethargy

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7
Q

which form of plague is the most common route of zoonosis?

A

Pneumonic form

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8
Q

What do you do when a patient has been diagnosed with plague?

A

NOTIFABLE - consult w/ county health dept or CDC

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9
Q

How is Yersinia pestis diagnosed?

A

PCR
FA test on culture

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10
Q

How is Yersinia pestis treated and prevented?

A

treated - tetracyclines, ahminoglycosides
prevented - flea prevention

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11
Q

what is the causative agent of Tularemia?

A

Francisella tularensis

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12
Q

Where is Francisella tularensis found?

A

northern hemisphere, mississippi/missouri river valley, mountain west, E/W coast

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13
Q

what are the reservoirs of Francisella tularensis biotype A and B?

A

A - rabbits and rodents
B - aquatic animals

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14
Q

How is Francisella tularensis transmitted?

A

aerosol - mowing over dead rodents
direct contact - rabbit hunters
ingestion
ticks

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15
Q

what are the clinical manifestations of Francisella tularensis? (including necropsy)

A

septicemia
cough
hepatic, splenic LN enlargement
necropsy - multifocal white foci of necrosis in liver, spleen

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16
Q

How is Francisella tularensis diagnosed?

A

exposure to wild rabbits/rodents/ticks
culture (notify lab - requires BSL3)
PCR

17
Q

what do you do when a patient has been diagnosed with tularemia?

A

NOFITY state/county health department

18
Q

How is Tularemia treated?

A

antibiotics - tetracyclines
control tick and fly populations

19
Q

What are the causative agents of Glanders and pseudoglanders?

A

glanders - Burkholderia mallei
pseudoglanders - Burkholderia pseudomallei

20
Q

what species is B. mallei commonly found in?

A

equids

21
Q

where is B. mallei endemic?

A

hot, humid areas
survives in soil and water for months

22
Q

How is B. mallei transmitted?

A

contact
inhalation
ingestion - contaminated feed/H20

23
Q

What are the clinical manifestations of acute B. mallei?

A

caseous/calcified centers
star-shaped scars

24
Q

what are the clinical manifestations of chronic B. mallei?

A

oronasal lesions
ulcerative lymphangitis

25
Q

How is B. mallei diagnosed?

A

culture
PCR

26
Q

How is B. mallei treated?

A

not curative - tetracyclines
euthanasia

27
Q

How is B. mallei prevented?

A

depopulation/euthanasia

28
Q

Where is B. pseudomallei found?

A

equatorial distribution
soil and surface water

29
Q

How is B. pseudomallei transmitted?

A

contaminated soil and water

30
Q

What are the clinical manifestations of B. pseudomallei in horses?

A

edema/lymphangitis

31
Q

How does B. pseudomallei infection present in goat and sheep?

A
32
Q

How is B. pseudomallei diagnosed?

A

culture
PCR

33
Q

How is B. pseudomallei treated?

A

often unsuccessful
euthanasia preferred

34
Q

How is B. pseudomallei prevented?

A

avoid muddy, fecal contaminated pastures
clean drinking water

35
Q

what is a clinical manifestation that is seen in B. mallei but not in B. pseudomallei?

A

calcified lesions

36
Q
A
37
Q
A

Microbiology (29 decks)

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