Actinomyces, Nocardia, Dermatophilus, Corynebacterium Flashcards
what are actinobacteria?
highly diverse group of G+ bacteria
cell morphology - coccoid to filamentous
what is the morphology of Actinomyces spp.?
rods or filaments
Are Actinomyces commensal or opportunistic bacteria?
opportunistic
what is Actinomycosis?
polymicrobial infection
Actinomyces is increased in mixed infections
what type of reactions are common in actinomycosis?
pyogranulomatous reactions
what does pyogranulomatous reactions contain?
suppurative inflammation
fistulous tracts secrete purulent exudate containing sulfur granules
What is seen with Actinomyces bovis and with what species?
lumpy jaw - seen in cattle
mandibular lymphadenopathy - horses
what is lumpy jaw?
indurated, suppurative lesions in soft tissue and bone
Osteomyelitis > tooth dislodgment, inability to chew, mandibular fractures
what is the causative agent?
Actinomyces bovis
What is seen with Actinomyces suis and with what species?
mastitis (lumpy udder)
swine
what is the causative agent?
Actinomyces suis
what causative agent often mimics strangles in horses?
Actinomyces bovis
what does Actinomyces viscosus cause and in what species?
subcutaneous abscesses
dogs and cats
what is the causative agent?
Actinomyces viscosus
what does the exudate from Actinomycosis contain?
sulfur granlues
what is this - collected from Actinomycosis exudate?
sulfur granules
club colonies with bacterial sized filaments
How is Actinomycosis diagnosed?
gram stain, culture and species ID, PCR, MALDI-TOF mass spec
With the Actinomyces species what should be cultured for the best chance of isolating pure cultures?
sulfur granules
How is Actinomycosis treated?
surgery (debridement), prolonged admin of antibiotics
How is bovine lumpy jaw treated?
sodium iodine IV with antibiotics, debridement of bone lesions w/ lavage of iodine solution
How do you prevent Actinomycosis?
good oral care, limit amount of rough forage fed, protect pets from grass awns
Is Dermatophilus congolensis commensal, opportunistic, or parasitic?
obligate parasite - grows on host
Can zoonotic transmission occur in Dermatophilus congolensis?
yes
How is Dermatophilus congolensis transmitted?
direct contact, fomites, and biting arthropods