Trueperella, Rhodococcus, Listeria, Erysipelothrix Flashcards
what phylum do Trueperella (Arcanobacterium) pyogenes and Rhodococcus equi belong to?
Actinobacteria
what phylum do Listera spp. and Erysipelothrix rhusiopathiae belong to?
Firmicutes
Trueperella spp.
gram - ?
morphology - ?
spore - ?
gram - positive
morphology - bacilli
spore - non-spore forming
Are trueperella spp. commensal or parasitic? what part of the body?
commensal - mucous membranes of mammals
what bacteria inhabits the upper respiratory, urogenital, and GI tracts of ruminants, swine, and other mammals and is a Actinobacteria?
Trueperella pyogenes
How does Trueperella pyogens become an opportunistic pathogen that causes disease?
traumatic inoculation, secondary infection
what type of lesions does T. pyogenes cause? where?
suppurative in many organs/tissues
what virulence factors does T. pyogenes have?
pyolysin O - cytotoxic to macrophages, neutrophils, RBCs
Neuraminidase - binds to host cell and extracellular matrix
what pathogen acts a synergistic pathogen in bovine liver abscesses?
T. pyogenes
How is T. pyogenes spread throughout the body?
Hematogenous dissemination
How does an infection with T. pyogenes present in swine?
septic arthritis - often after farrowing
How does an infection with T. pyogenes present in cattle?
severe mastitis - often heifers and dry cows
what is this cow most likely infected by?
T. pyogenes
How is T. pyogenes transmitted?
horn flies, teat contact with contaminated environment or contaminated milking equipment
How is T. pyogenes diagnosed?
presumptive - clinical findings and gram + rods in exudate smear
definitive - culture & species ID of bacterium from clinical samples
What type of T. pyogenes infections do not respond well to antibiotics?
in vivo (abscess encapsulation)