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Microbiology > Bordetella/Campylobacter > Flashcards

Bordetella/Campylobacter Flashcards

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Biology 101 flashcards
1
Q

where is Bordetella spp found?

A

extracellular commensal in upper respiratory tract of mammals and birds

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2
Q

what are the 3 opportunistic pathogens of Bordetella we discuss?

A

B. bronchiseptica, B. avium, B. parapertussis

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3
Q

Describe Bordetella - FYI
gram -
oxygen requirements -
catalase/oxidase -

A

gram - negative
oxygen requirements - obligate aerobe
catalase/oxidase - positive

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4
Q

How is Bordetella transmitted?

A

aerosol transmission

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5
Q

what does it mean that Bordetella is biphasic?

A

avirulent at 25 C
virulent genes switched at 37 C

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6
Q

what are the factors that contribute to kennel cough being multifactorial?

A

stress
bordetella bronchiseptica
canine pneumovirus

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7
Q

what does Bordetella have a tropism for?

A

ciliated respiratory epithelium

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8
Q

what are the toxin virulence factors for Bordetella?

A
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9
Q

what does B. bronchiseptica cause in pigs and dogs?

A

pigs - atrophic rhinitis
dogs - canine infectious tracheobronchitis

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10
Q

what does B. avium cause in turkeys?

A

Coryza

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11
Q

what are the clinical signs of kennel cough?

A

coughing, retching, mild serous oculonasal discharge, respiratory infections, bronchopneumonia

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12
Q

what is canine infectious tracheobronchitis?

A

kennel cough

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13
Q

what causes turbinate hypoplasia in pigs (atrophic rhinitis)?

A

infection with Brodetella bronchiseptic and Pasteurella multocida

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14
Q

what are the clinical signs of turkey coryza?

A

beak breathing, sneezing

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15
Q

How is Bordetella bronchiseptica in dogs diagnosed?

A

Is the dog coughing/sneezing?
history - boarding kennels, dog parks, veterinary hospitals
Positive ID (culture/PCR)
treacheal fluids, sinus exudates, PCR (CDV, Mycoplasma)

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16
Q

How is Bordetella bronchiseptica in dogs treated?

A

vaccination
isolation/improved hygiene
supportive care +/- antibiotiocs

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17
Q

what organisms may be recovered from cases of canine kennel cough?

A
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18
Q

what species of Bordetella produce disease in respective hosts - dogs, pigs, turkeys?

A
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19
Q

what are the possible clinical presentations of Bordetella infections in animals?

A
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20
Q

where does Campylobacter spp. infect?

A

intestinal and genital tracts

21
Q

what type of disease does Campylobacter spp. commonly cause?

A

diarrhea or abortion

22
Q

what does C. fetus subsp. venerealis cause in cattle?

A
23
Q

what does C. fetus subsp. fetus cause in sheep?

A
24
Q

what disease does C. jejuni cause?

A
25
Q

what Campylobacter species cause venereal disease?

A

C. fetus, C. venerealis, or C. jejuni

26
Q

what campylobacter species cause diarrheal disease?

A

C. jejuni

27
Q

what are the important virulence factors of Campylobacter spp.?

A
28
Q

What does the microcapsule do in Campylobacter spp.?

A

reduces susceptibility to complement and phagocytosis

29
Q

What does the S-layer do in Campylobacter spp.?

A

8 variants for immune evasion

30
Q

what is seen with Bovine genital campylobacteriosis?

A

temporary infertility
abortion
asymptomatically infected carriers

31
Q

what can cause permanent infertility in cattle? how?

A

C. venerealis
bacteria migrate to oviducts

32
Q

what is seen with Ovine genital campylobacteriosis?

A

abortion in ewes
necrotic placentitis

33
Q

what causes Bovine genital campylobacteriosis?

A

C. venerealis

34
Q

what causes ovine genital campylobacteriosis?

A

C. fetus

35
Q

what is seen with canine intestinal campylobacteriosis?

A

most infections subclinical
enteritis

36
Q

what causes canine intestinal campylobacteriosis?

A

C. jejuni

37
Q

what causes avian vibrionic hepatitis?

A

C. jejuni

38
Q

How is Campylobacter spp. diagnosed?

A

PCR and culture

39
Q

How is C. fetus treated?

A

therapeutic vaccination
chlortetracycline

40
Q

How is C. venerealis treated?

A

Dihydrostreptomycin in cattle

41
Q

How is C. jejuni treated?

A

Dihydrostreptomycin
fluids and antibiotics

42
Q

what are some important virulence factors carried by Bordetella and their pathogenic effects?

A

Focus on toxins

43
Q

How are Bordetella infections commonly treated in each animal species it affects?

A

vaccination
isolation/improved hygiene
supportive care +/- antibiotics

44
Q

what are the common Campylobacter species and what animals do they affect?

A

C. fetus subsp, veneralis - bovine
C, fetus subsp. fetus - ruminants (lambs)
C. jejuni - most species (dogs)

45
Q

what are the clinical presentation of Campylobacter in animal species?

A
46
Q

How do Campylobacter avoid immune detection?

A

microcapsule resist complement and phagocytosis
S layer shifts antigenic features

47
Q

How is Campylobacter diagnosed in animals?

A

culture and PCR

48
Q

what are the treatment or prevention options available for campylobacter in animals?

A

vaccination, antibiotics (dihydrostreptomycin, chlortetracycline), supportive care

Microbiology (29 decks)

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