Wk4 Small intestine/Colon Pathology Flashcards by Weston Tardy

Q

Most common cause of acute diarrhea:

A

infectious

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Q

Two types of inflammatory bowel disease:

A

ulcerative colitis

Crohn’s

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Q

Inflammatory changes involving mucosa and submucosa

limited to colon and rectum

A

Ulcerative colitis

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Q

Transmural inflammatory changes

any area of GI tract

“skip lesions”

A

Crohn’s

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Q

Pseudopolyps

A

UC

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Q

Ulcerations

Fissures

A

Crohn’s

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Q

Branched crypts

A

UC

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Q

non-caseating granulomas

A

Crohn’s

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Q

Cobblestone

A

Crohn’s

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Q

Creeping fat

Fistulas

A

Crohn’s

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Q

bloody diarrhea with mucus

A

UC

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Q

presentation of Crohn’s

A

variable

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Q

ASCA positive

A

Crohn’s

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Q

pANCA positive

A

UC

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Q

Toxic megacollon

A

UC

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Q

Small bowel strictures

perforation

fistulas

A

Crohn’s

Q

Long term complication of UC and CD

A

intestinal adenocarcinoma

Q

colitis after surgery

A

diversion colitis

Q

cause of diversion colitis

A

loss of short chain fatty acids

Q

chronic watery diarrhea with normal colonoscopy

A

microscopic colitis

Q

Two types of microscopic colitis:

A

lymphocytic

2. collagenous

Q

Mechanism of microscopic colitis:

A

autoimmune

Q

Mucosal patchy erythema

telangiectasias

A

Radiation enterocolitis

Q

pneumonitis intestinalis

air bubbles

A

neonatal necrotizing enterocolitis

Q

apoptotic cell death in crypts without inflammation

A

graft vs host disease

Q

unexplained constipation or diarrhea

A

Irritable Bowel Syndrome

Q

Common locations of Ischemic bowel disease:

A

watershed zones

splenic flexure

sigmoid colon

Q

atrophy of surface epithelium

coagulative necrosis

possible sepsis

A

Ischemic bowel disease

Q

Risk factor for ischemic bowel disease

A

cardiac or vascular disease

Q

malformed mucosal and submucosal blood vessels

A

Angiodysplasia

Q

caused by elevated intraluminal pressure in the sigmoid colon

A

Sigmoid diverticulitis

Q

malfunction in puborectalis muscle

A

solitary rectal ulcer syndrome

Q

fibromuscular dysplasia of lamina propria

A

solitary rectal ulcer syndrome