Weight Loss

Question 1

When to use obesity Drugs

Answer 1

BMI of 30 kg/m2 or 27 with comorbid conditions

Question 2

contraindications

Answer 2

pregnancy, Cardiac disease, HTN, anorexia or history of, closed angle glaucoma, general anesthesia

Question 3

Orlistat

Answer 3

gastric and pancreatic lipase inhibitor

Question 4

Orlistat indications

Answer 4

obesity management, weight loss and maintenance in patients who do not feel hungry, that eat out often, have increased CV disease risk

Question 5

Orlistat contraindications

Answer 5

pregnancy, malabsorption disorders, cholestasis, calcium oxalate kidney stones, anorexia, organ transplant

Question 6

Orlistat ADR

Answer 6

Diarrhea, Steatorrhea, oily spotting, flatulence with fecal discharge, oily stools, HA

Question 7

Orlistat serious ADR

Answer 7

hypersensitivity, angioedema, Vit def, lower GI bleed

Question 8

Orlistat drug interactions

Answer 8

Warfarin, cyclosporine, amiodarone, AEDs, fat soluble vits and thyroid hormone

Question 9

Lorcaserin MOA

Answer 9

serotonin receptor agonist. that increases satiety

Question 10

Lorcaserin warnings

Answer 10

serotonin syndrome, valvular heart disease, cognitive impairment, psychiatric disorders, suicide, monitor blood glucose

Question 11

Lorcaserin interactions

Answer 11

serotonin drugs (triptans, MAOIs, SSRI, SNRI, dextromethorphan

Question 12

Lorcaserin ADR

Answer 12

HA, dizziness, fatigue, nausea, dry mouth, dry eye, constipation/diarrhea, cough, bradycardia, hyperprolactinemia

Question 13

Naltrexone/bupropion (contrave) MOA

Answer 13

Nalterxone=opioid antagonist; Bupropion=antidepressant?

Question 14

Contrave indications

Answer 14

weight loss in obesity or overweight with comorbidity

Question 15

Contrave indications

Answer 15

uncontrolled htn, seizures, chronic opioid use, use of MAOI

Question 16

Contrave ADR

Answer 16

NVD, constipation, HA, dizziness, insomnia, dry mouth

Question 17

Contrave warningsq

Answer 17

suicide, seizure, htn, tachy, liver dysfunction, angle closure glaucoma

Question 18

Qsymia MOA

Answer 18

Phentirmine/topiramate

Question 19

Qsymia contraindications

Answer 19

pregnancy, glaucoma, hyperthyroid

Question 20

Qysmia warnings

Answer 20

increased HR, Suicide, Acute myopia and secondary angle closure glaucoma, cognitive impairment, metabolic acidosis, elevated creatinine, hypoglycemia

Question 21

Qysmia interactions

Answer 21

Oral contraceptives (spotting), CNS depressants, non-potassium sparing diuretics

Question 22

Liraglutide MOA

Answer 22

GLP1 agonist, increases satiety

Question 23

Liraglutide ADR

Answer 23

N, bloating, constipation

Question 24

Phentermine MOA

Answer 24

sympathomimetic similar to aphetamines, stimulates CNS activity. for people that think about being hungry. appetite suppressant

Question 25

Phentermine Indications

Answer 25

short term treatment

Question 26

Phentermine contraindications

Answer 26

MAOI, arteriosclerosis, CV disease, hyperthyroidism, glaucoma, agitation, HX of drug abuse, pregnancy, breastfeeding

Question 27

Phentermine serious ADR

Answer 27

dependency, psychosis, tachy, HTN, pulm htn, valvular heart disease

Question 28

Phentermine ADR

Answer 28

palpitations, restlessness, insomnia, diarrhea, xerostomia, HTN, euphoria, HA

Question 29

Phentermine interactions

Answer 29

MAOI, linezolid, effexor

Question 30

Diethylpropion

Answer 30

sympathomimetic

Question 31

Diethylpropion ADR

Answer 31

dry mouth, D/C, restlessness, anxiety, insomnia, HA, HTN

Question 32

Phendimetrazine

Answer 32

sympathomimetics

Question 33

Off label drugs

Answer 33

Desvenlafaxine, Sprionolactone, pindolol

Question 34

Lisdexamfetamine indications

Answer 34

binge-eating disorder

Question 35

Lisdexamfetamine MOA

Answer 35

sympathomimetic