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Pharmacology > Fibromyalgia > Flashcards

Fibromyalgia Flashcards

1
Q

Milniciprain (Savella) MOA

A

SNRI selective serotonin and norepinephrine uptake inhibitor

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2
Q

Milnicipran warnings

A

suicide, serotonin syndrome, elevated BP, tachycardia

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3
Q

Milnicipran ADR

A

NV, palpitations, tachychardia, HA, constipation, hyperhidrosis, dizziness

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4
Q

Cyclobenzaprine MOA

A

skeletal muscle relaxant. potentiates NE and anticholinergic activity

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5
Q

Cyclobenzaprine indications

A

adjunct to rest and PT for relief of muscle spasm

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6
Q

Milnicipran indications

A

fibromyalgia

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7
Q

Fibromylagi drugs

A

Milniciprain, pregabalin, Duloxetine

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8
Q

Cyclobenzaprine ADR

A

Cholinergic SE, angle closure glaucoma, urinary retention

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9
Q

Cyclobenzaprine interactions

A

MAOI, EtOH, tramadol seizure risk

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10
Q

Carisoprodol indications

A

acute treatment for muscle spasms

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11
Q

Carisoprodol ADR

A

restlessness, insomnia, anxiety, muscle twitches, incoordination, loss of appetite, NC, agitation, hallucination, seizures

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12
Q

Metaxalone indications

A

muscle relaxant

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13
Q

Metaxalone interactions

A

CNS depressants

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14
Q

Metaxalone ADR

A

drowsiness, dizziness, HA, nervousness, NV, GI upset, leukopenia, hemolytic anemia, jaundice

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15
Q

Baclofen MOA

A

GABA analog

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16
Q

Baclofen indications

A

muscle spasms due MS, spinal cord injury, trigeminal neuralgia, off label as adjucant for cancer pain

17
Q

Baclofen ADR

A

drowsiness, dizziness, weakness, fatigue,

18
Q

Orphenadrine MOA

A

anticholinergic

19
Q

Orphenadrine ADR

A

dry mouth, tachycardia, palpitation, urinary retention, blurred vision, mydriasis, ocular pressure, weakness, NC

20
Q

Glucosamine Sulfate

A

natural amino sugar stimulates metabolism of chondrocytes in articular cartilage and synovial cells in synovial tissues

21
Q

Glucosamine Sulfate ADR

A

mild, some GI

Pharmacology (33 decks)

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