Fibromyalgia Flashcards
Milniciprain (Savella) MOA
SNRI selective serotonin and norepinephrine uptake inhibitor
Milnicipran warnings
suicide, serotonin syndrome, elevated BP, tachycardia
Milnicipran ADR
NV, palpitations, tachychardia, HA, constipation, hyperhidrosis, dizziness
Cyclobenzaprine MOA
skeletal muscle relaxant. potentiates NE and anticholinergic activity
Cyclobenzaprine indications
adjunct to rest and PT for relief of muscle spasm
Milnicipran indications
fibromyalgia
Fibromylagi drugs
Milniciprain, pregabalin, Duloxetine
Cyclobenzaprine ADR
Cholinergic SE, angle closure glaucoma, urinary retention
Cyclobenzaprine interactions
MAOI, EtOH, tramadol seizure risk
Carisoprodol indications
acute treatment for muscle spasms
Carisoprodol ADR
restlessness, insomnia, anxiety, muscle twitches, incoordination, loss of appetite, NC, agitation, hallucination, seizures
Metaxalone indications
muscle relaxant
Metaxalone interactions
CNS depressants
Metaxalone ADR
drowsiness, dizziness, HA, nervousness, NV, GI upset, leukopenia, hemolytic anemia, jaundice
Baclofen MOA
GABA analog
Baclofen indications
muscle spasms due MS, spinal cord injury, trigeminal neuralgia, off label as adjucant for cancer pain
Baclofen ADR
drowsiness, dizziness, weakness, fatigue,
Orphenadrine MOA
anticholinergic
Orphenadrine ADR
dry mouth, tachycardia, palpitation, urinary retention, blurred vision, mydriasis, ocular pressure, weakness, NC
Glucosamine Sulfate
natural amino sugar stimulates metabolism of chondrocytes in articular cartilage and synovial cells in synovial tissues
Glucosamine Sulfate ADR
mild, some GI
