Aminoglycosides Flashcards

1
Q

Aminoglycosides

A

gentamicin, tobramycin, amikacin, streptomycin, neomycin

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2
Q

MOA

A

inhibits protein synthesis at the 30s ribosomal subunit

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3
Q

Spectrum

A

primarily gram (-)

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4
Q

indications

A

pyelonephritis, severe UTI, HAP, meningitis, peritonitis, sepsis, ophthalmic/otic

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5
Q

ADR

A

ototoxicity, nephrotoxicity

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