Aminoglycosides Flashcards
1
Q
Aminoglycosides
A
gentamicin, tobramycin, amikacin, streptomycin, neomycin
2
Q
MOA
A
inhibits protein synthesis at the 30s ribosomal subunit
3
Q
Spectrum
A
primarily gram (-)
4
Q
indications
A
pyelonephritis, severe UTI, HAP, meningitis, peritonitis, sepsis, ophthalmic/otic
5
Q
ADR
A
ototoxicity, nephrotoxicity