Oxazolidinones Flashcards
1
Q
Oxazolidinones
A
linezolid, Tidezolid
2
Q
MOA
A
inhibits cell wall synthesis by binding at the 50s ribosomal subunit
3
Q
Spectrum
A
activity against gram (+) staph, strep, enterococcus, anaerobic bacilli, cocci
4
Q
indications
A
HAP, CAP, VRE, SSTI
5
Q
ADR
A
NVD, pancytopenia, HA, lactic acidosis
6
Q
Lipoglycopeptides
A
oritavancin, dalbavancin
7
Q
Lipglycopeptides MOA
A
interferes with cross linking of peptidoglycan in bacterial cell walls
8
Q
Lipoglycopeptides indications
A
acute bacterial skin and skin structure infections
9
Q
Mupirocen
A
impetigo, intranasal MRSA colonization
10
Q
Quinupristin-dalfopristin
A
serious or life threatening vancomycin resistant enterococcus infections, complicated SSTI
11
Q
colistin
A
last line!
