fluoroquinolones Flashcards
1
Q
Fluoroquinolones
A
levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin,
2
Q
MOA
A
inhibit DNA gyrase and topoisomerase
3
Q
ciprofloxacin spectrum
A
gram (-) aerobic rods
4
Q
ciprofloxacin indications
A
LRI, intra-abd, UTI, infectious diarrhea, SSTI, anthrax
5
Q
Levofloxacin spectrum
A
gram (-), gram (+) s, aureus (MRSA), S. pneumonia, legionella
6
Q
levofloxacin indications
A
chronic bronchitis and CAP, SSTI, intra-abd
7
Q
Moxifloxacin spectrum
A
gram (-), gram (+) S. aureus (MRSA), S. pneumoniae, M. tuberculosis, gram (-) anaerobes
8
Q
Moxifloxacin indications
A
plague
9
Q
Gatifloxacin indication
A
bacterial conjunctivitis
10
Q
ADR
A
joint cartilage injury in peds, long QT, NVD, HA, dizziness, confusion, tendinitis, polyneuropathy