fluoroquinolones Flashcards

1
Q

Fluoroquinolones

A

levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin,

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2
Q

MOA

A

inhibit DNA gyrase and topoisomerase

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3
Q

ciprofloxacin spectrum

A

gram (-) aerobic rods

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4
Q

ciprofloxacin indications

A

LRI, intra-abd, UTI, infectious diarrhea, SSTI, anthrax

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5
Q

Levofloxacin spectrum

A

gram (-), gram (+) s, aureus (MRSA), S. pneumonia, legionella

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6
Q

levofloxacin indications

A

chronic bronchitis and CAP, SSTI, intra-abd

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7
Q

Moxifloxacin spectrum

A

gram (-), gram (+) S. aureus (MRSA), S. pneumoniae, M. tuberculosis, gram (-) anaerobes

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8
Q

Moxifloxacin indications

A

plague

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9
Q

Gatifloxacin indication

A

bacterial conjunctivitis

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10
Q

ADR

A

joint cartilage injury in peds, long QT, NVD, HA, dizziness, confusion, tendinitis, polyneuropathy

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