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Pharmacology > Tetracyclines > Flashcards

Tetracyclines Flashcards

1
Q

Tetracyclines

A

Tetracycline, doxycycline, demeclocycline, minocycline, tigeclycline

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2
Q

MOA

A

inhibit protein synthesis by binding at the 30s ribosomal subunit. bacteriostatic

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3
Q

Spectrum

A

Broad spectrum

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4
Q

tetracycline Indications

A

URI, LRI, SSTI, rickettsia infections, malaria prophylaxis,

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5
Q

Doxycycline indications

A

acne and rosacea, lyme and vibrio, Anthrax

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6
Q

Tigecycline indications

A

complicated SSTI and intra-abd infections

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7
Q

ADR

A

Tooth discoloration, photosensitivity, NVD, Jarisch-herxheimer rxn

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8
Q

doxycycline ADR

A

black hairy tongue

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9
Q

Minocycline ADR

A

skin pigmentation (greyish)

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10
Q

demeclocycline indication

A

primarily for SIADH

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Pharmacology (33 decks)

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