Macrolides Flashcards
1
Q
Macrolides
A
erythromycin, azithromycin, telithromycin, clarithromycin, fidaxomycin, cethromycin
2
Q
MOA
A
inhibit bacterial protein synthesis at 50s ribosomal subunit
3
Q
Spectrum
A
not strep pneumo! Gram (+) staph and strep, corynebacteria, mycoplasma, legionella, listeria. Gram (-) neissaria, bordetella, bartonella, treponema, campylobacter, H. pylori, H. flu
4
Q
Indications
A
respiratory, AOM, strep pharyngitis, SSTI, Chlamydia, pertussus, diptheria, GI,
5
Q
ADR
A
Long QT, stevens-johnson syndrome, TEN
