W15_06 bipolar disorder Flashcards
note: decreased need for sleep is a hallmark symptom of mania
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what are the symptoms of mania? GSTPAID
grandiosity;
sleep (need less);
talkative;
painful (consequences);
activity (increased goal-directed activity)/psychomotor agitation;
ideas (flight of);
distractibility
how long do manic symptoms have to last to fulfill mania criteria?
1 week
what’s the difference between hypomania and mania
4 days;
criteria for mania are the same;
hypomania episode is not severe enough to cause impairment in social/occupational functioning
what’s the difference between bipolar I and bipolar II?
if there’s 1 manic episode, then patient is bipolar I
prevalence of bipolar disorder?
bipolar I: 1%;
bipolar II: 1.1%
note:
bipolar patients spend more time being depressed than being manic. About half of the time, they are asymptomatic
is there a genetic component of bipolar disorder?
yes
note: there are cognitive deficits associated with patients with bipolar disorder
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note: bipolar disorder is often misdiagnosed
unipolar depression, anxiety disorders, schizophrenia, personality disorder, alcohol abuse/dependence
what’s the treatment for bipolar disorder?
pharmacotherapy;
psychosocial therapy
what does IPSRT stand for?
interpersonal social rhythm therapy
what’s the difference between IPSRT vs IPT?
IPSRT for bipolar;
IPT for depression
note: good to do investigations before starting psychiatric treatment to get a baseline of their organ functions
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what’s CANMAT?
canadian network for mood and anxiety treatments
first line therapies for bipolar 1 depression?
lithium, lamotrigene, quetiapine (antipsychotics are used to treat seizures, mood problems), and more
first line therapies for bipolar 1 mania?
lithium, divalproex, risperidone, and more
first line therapies for bipolar 1 maintenance?
lithium, lamotrigine, divalproex, and more
what does lithium do?
gold standard that treats all three phases of bipolar;
small therapeutic index with lots of side effects. Renally cleared, so take into account any water pills
what’s divalproex?
anticonvulsant used in mania and maintenance phases of bipolar
what’s lamotrigine?
anticonvulsant used in depression phase of bipolar;
risk of steven-johnson syndrome
note: atypical antipsychotics show some evidence for treating all three phases of bipolar disorder
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