W10_03 menstrual cycle and disorders of menstruation Flashcards

1
Q

when do ovulatory periods start after menarche?

A

usually 12 months, but up to 3 years

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2
Q

what’s the length of the menstrual cycle?

A

28 d (24-32)

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3
Q

what’s the length of menstruation?

A

3-7 days

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4
Q

note: for endometrial development, menses begins in the follicular phase. Then?

A

Menses moves into the proliferative phase. At the onset of ovulation, it then moves into the secretory phase

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5
Q

what’s the staging of follicular development?

A

follicular phase - ovulation - luteal phase

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6
Q

estrogen is like the fertilizer that makes the grass grow. What is progesterone?

A

the lawn mower that cuts the grass down (in follicular phase)

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7
Q

inhibin A falling causes what?

A

rise in FSH

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8
Q

inhibin B and estradiol increase causes what?

A

negative feedback to FSH

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9
Q

what causes LH to rise?

A

estrogen increase - positive feedback

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10
Q

how does selection for a single follicle work?

A

it’s bigger, has more granulosa cells, and can aromatize androgens better. Thus, it inhibits all the other cells from growing

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11
Q

when does the oocyte get released after the LH surge?

A

36 hours (35-44)

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12
Q

what’s spinnbarkeit?

A

clear mucus discharge that’s a sign of the cycle - will be there just before the egg releases

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13
Q

what’s molimina?

A

premenstrual syndrome; caused by progesterone

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14
Q

when does the oocyte release on a basal body temperature graph?

A

there’s a dip in temp - JUST after the rise in temp is the release

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15
Q

how many days is the luteal phase?

A

14 days! (if it’s not, then something’s wrong)

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16
Q

what’s the main hormone in luteal phase?

A

progesterone. If pregnant, it’ll stay. If not, it’ll go

17
Q

in the luteal phase, how do inhibin A, estradiol, progesterone behave?

A

all high. Progesterone and estradiol inhibit FSH so no folliculogenesis

18
Q

corpus luteum stops producing what, in the case of no pregnancy?

A

inhibin A and progesterone

19
Q

what’s a normal amount of blood loss in menstruation?

A

25-60 mL

20
Q

what’s the mechanism of endometrial shedding?

A

lack of progesterone causes constriction of the spiral arteries - ischemia/necrosis