Vitamin D

Question 1

it is called the the “Sunshine vitamin” which acts as a steroid hormone; Anti-rachitic or ricket preventive vitamin

Answer 1

Vitamin D

Question 2

Other name for vitamin D

Answer 2

(Calciferol)

Question 3

Precursors of VIt D in plants

Answer 3

Ergosterol

Question 4

Precursors of VIt D in animals

Answer 4

7-dehydrocholesterol

Question 5

Sources of vit D

Answer 5

fish liver oils (sardines, salmon and herring)

Question 6

Poor sources of vit D

Answer 6

Human milk and unfortified cow’s milk

Question 7

inactive form of vitamin D in the skin

Answer 7

7-dehydrocholesterol

Question 8

predominant in circulating metabolite;

product of vit D hydroxylation in the liver.

Answer 8

25-hydroxyvitamin D3 or calcidiol

Question 9

most active/Potent form of vitamin D

Answer 9

1,25 dihydroxyvitamin D3 or calcitriol

Question 10

hormones that activates vitamin D

Answer 10

Parathyroid hormone

Question 11

Upon UV exposure of ergosterol it turns into _____

Answer 11

Ergocalciferol

Question 12

Upon hydroxylation of 7-dehydrocholesterol it turns into ______

Answer 12

Cholecalciferol

Question 13

Ca binding protein

Answer 13

Calbindin

Question 14

Functions of Vitamin D:

Answer 14

1. Facilitates the absorption of calcium during low dietary calcium intake
2. Maintenance of calcium and phosphorus homeostasis
3. cell differentiation/cell proliferation

Question 15

acts as a hormone binding VDR (vit D receptor proteins) in the nucleusregulates gene expression

Answer 15

Calcitriol

Question 16

Vitamin D Deficiency : a syndrome (abnormal muscle twitching, cramps, spasms in the wrists and joints)

Answer 16

Tetany

Question 17

Vitamin D Deficiency in children

Answer 17

RICKETS

Question 18

Vitamin D Deficiency in Adults

Answer 18

OSTEOMALACIA

Question 19

A disease involving impaired mineralization of the bone
bone pain, muscular tenderness, hypocalcemic tetany
enlargement of the epiphyses of the long bone and rib cage, bowing of the legs, bending of the spine and weak and toneless muscles

Answer 19

Rickets
Knock knees
Rachitic rosary

Question 20

Vitamin D Toxicity: (more than 25 μg/day (infants & small children) and 50 μg/day (adults)
◦elevated serum calcium and phosphorus, calcinosis of kidney, lungs, ear

Answer 20

Hypervitaminosis D

Question 21

Signs of Excessive Vitamin D Toxicity

Answer 21

Excessive calcification of bone
Kidney stones
Hypercalcemia
Headache

Question 22

Signs of Excessive Vitamin D Toxicity

Answer 22

Weakness
Nausea and vomiting
Constipation
Polyuria
Polydipsia/extreme thirstiness