Food and Drug Interaction Pt. 2

Question 1

induce hepatic enzymes

Answer 1

Anticonvulsants

Question 2

Vit B6 conversion

Answer 2

Anti tuberculosis drugs

Question 3

Side effects of vitamin B6 (pyridoxine)

Answer 3

Peripheral neuropathy

Question 4

Food Sources of Vitamin B6

Answer 4

Green leafy vegsFruits – banana melons and dried

fruits, NUTS

Question 5

EXCELLENT SOURCES vitamin B6

Answer 5

LIVER , GLANDULAR ORGANS, POULTRY

MEAT , FISH , SHELLFISHES

Question 6

Drug Effects on Nutrition: Metabolism
Methotrexate
pyrimethamine

Answer 6

• May treat with folinic acid or folic acid
  supplements
• Folic acid antgonist

Question 7

is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments.

Answer 7

Methotrexate

Question 8

is a medication used with leucovorin to treat the parasite diseases toxoplasmosis and cystoisosporiasis.

Answer 8

pyrimethamine/Daraprim

Question 9

Drug Effects on Nutrition: Excretion

Loop diuretics

Answer 9

• increase excretion of potassium, magnesium,
  sodium, chloride, calcium
  – Patients may need supplements with long term
  use, high dosages, poor diets
  – Electrolytes should be monitored

Question 10

Loop diuretics

Answer 10

(furosemide, bumetanice)

Question 11

Potassium content of Banana 1 piece (114 grams)

Answer 11

451 mg

Question 12

Drug Effects on Nutrition: Excretion

CORTICOSTEROIDS

Answer 12

-Decrease sodium excretion resulting in water retention
-Increase excretion of
Potassium
Sodium
Low Sodium ,
High Sodium Diet Is recommended

Question 13

Drug Side Effects that Affect Nutritional Status

Answer 13

• Appetite changes
• Oral taste and smell
• Nausea
• Dry mouth
• Gastrointestinal effects
• Organ system toxicity
• Glucose levels

Question 14

Drugs That May Increase Appetite

Answer 14

• Anticonvulsants
• Hormones
• Psychotropic drugs
—Antipsychotics
—Antidepressants, tricyclics, MAOIs

Question 15

Drugs that Affect the GI Tract

Alendronate (Fosamax)

Answer 15

anti-osteoporosis
drug—patients must sit upright 30 minutes
after taking it to avoid esophagitis

Question 16

Drugs that Affect the GI Tract

Aspirin or other NASAIDs

Answer 16

can cause GI bleeding, gastritis

Question 17

Drugs that Affect the GI Tract

Orlistat

Answer 17

blocks fat absorption, can cause oily

spotting, fecal urgency, incontinence

Question 18

Drugs that Affect the GI Tract

Narcotic agents cause

Answer 18

constipation

Question 19

Non Nutritive Components-drug excipients

Answer 19

SORBITOL

Question 20

“ SWEETENING AGENT “ FOUND IN A WIDE VARIETY OF FRUITS

Answer 20

SORBITOL

Question 21

live micro organisms containing

potentially beneficial bacteria or yeast.

Answer 21

PROBIOTICS

Question 22

Sorbitol induced _______ symptoms

Answer 22

abdominal

Question 23

Balls of UNABSORBED MATERIAL residing in the
stomach , may form undissolved portions of drugs and
from masses of food matter , in particular plant fibers
(PHYTOBENZOARS).”

Answer 23

BENZOARS

Question 24

TYPICAL DRUGS found in benzoars:

Answer 24

SUCRALFATE
CHOLESTYRAMINE
ALUMINUM HYDROXIDE GEL
IRON AND ANTACID TABLETS

Question 25

FOODS TO BE AVOIDED FOR

PREVENTION OF BENZOAR FORMATION

Answer 25

Apples , Berries,
Brussels sprout,
Coconuts, Figs, 
Oranges, Grapefruits,
Persimmons, Potato 
skins,

Question 26

Drugs that Affect the GI Tract

Answer 26

Alendronate (Fosamax)
Aspirin or other NASAIDs
Orlistat
Narcotic agents