Vibrios and climate change Flashcards
the kyoto protocol
The Kyoto Protocol is an international agreement linked to the United Nations Framework Convention on Climate Change, which commits its Parties by setting internationally binding emission reduction targets
when was the kyoto protocol adopted
11 dec 1997, entered into force in 2005
how many countries committed to kyoto protocol
37 all agreed to reduces GHG emission to an average of 5% again 1990 levels.
a later commitment period committed t reduce GHG by
at least 18% below 1990 levels in the eight year period from 2013-2020. (comp of parties in second commitment is diff to first)
main target
to limit global warming to 2.52 degrees by 21000
by understanding climate change we can predict
whens he next outbreak of disease will be, what strain it will be- fundamental in our battle against pathogens
cholera and climate change
we can create models which actively predict cholera outbreaks before they occur
why would it be helpful if could make predictions about the next utbreak
manage resources which cane mobilised for treatment and effected individuals. Appropriate antibiotics and vaccines can be given
interrelationships o environment and mcirobes
pH, gas, nutrients, temperature, the seas and oceans
long term enviroenmtneal changes
global warming
changing climete
sometimes short term e.g. seasonal
annual biannual ocean temp
El Nino
El Niño- soutern Osciliation (ENSO)
disruption of the ocean atmosphere system in the tropical pacific every few years in dec- warming of water in western america
El Nino triggers what sort of global weather patters
- trade winds relax in central and eastern pacific
- reduced upwelling of nutrients and oil water in eastern pacific leading to rise in SST
- increased rain fall in southern USA and Peru
- drought in west pacific (australia, indonesia)
SST
seas surface temperature
ENSO is considered
long most important driver of climate variations globally
in El Nino years there is
more extreme weathers
why are there no longer cholera outbreaks in exeter and in london, in comparison to the 1800?
- clean drinking water?
- draining?
- better sanitary conditions?
- better health and diet?
environmental parameter that would make cholera outbreak more probable in exeter or london etc?
climate change
which ar et most studied group o diseases affected by climate change
vector born diseases
vector population nd amplification of pathogen in host is affected by
variation in weather/cliate
could seasonal cold/ flu be due t change in
weather?
ecological disturbance (weather/climate)
can cause humans to be in greater contact with vectors due to havitat
malaria is thought to be on the decrease in Africa because of
changing weather, temp, humidity
vibrio species of clonal significance
V.cholerae, V. parahaemolyticus, V.vulnificus
V cholerae has
2 main serotypes, last pandemic 1883
V.parahemolyticus is a
food broke disease- last pandemic 1996
V.vulnificus
necrotising fascitis
Brio parahaemolyticus symptoms
bloody stool, die from severe dehydration.
what causes symptoms of Vibrio parahemolyticus
toxin production which disturbs the integrity of the bowel
treatment of Vibrio parahaemolyticus
Oral rehydration therapy
vibrio vulnificus symtoms
necrotising fasciitis caused by wound infection- responsible for 95% of all seafood related deaths in SA and also fisherman wounds- very quickly a terrible infection occurs
between 1989-2004 how many deaths caused by Vibrio vulnificus
207
ocean warming and bacterial growth
deeply influential
an increasing suave temp triggers
algal bloom that promotes an increase in zooplankton feeding on algae. Vibrio adhere to copepods which eat the algae- using the chitin.
the ore algae, the more
copepods,
the more copepod
the more copepods from vibrio to adhere to- forming biofilms
therefore when a storm occurs
there is an influx of cholera ridden water rom the sea to low areas of land- using cholera outbreak
basic
as the oceans warm there is an increase in phytoplankton due to increased growth, this causes the zooplankton commits to grow. The oceans warming also increases growth of bacteria and since there are more copepods, more human and animal related disease
very few cases of irbio are actually
correctly identified and reproted/ data is not mate international available to Vibrio community
invisible cases of vibirio
- data ot and publicly available to vibrio community
- vibrio not notifiable as agent
- no formal identification of agent responsible
- misdiagnois
- cases not serious, therefore not reported