essay plans- brief Flashcards
1
Q
diversity of primary and opp fungal pathogens and risk to the host
A
- opp pathogens
-less severe app disease - more severe app disease
primary pathogens
-Histoplasmosis
-blastomycosis
-dissemination risk
-immunocomprpmised host
2
Q
types of gunnel infection and range of antifungals
A
-intro
-superfiical
-subcutansous
-invasive opp and primary
-polyenes
azoles
allyamines
-echinocandins
-flucytosine
-conc
3
Q
anti-virulence factors in controlling disease
A
- virulence factors are molecular determinants of disease
- pilli on bacteria
- inhibting secretary system- YscN, SP-1
- targeting quorum sensing
- reduced virulence- antitoxin vaccines
- increased virulence
- conclusion
4
Q
antibiotics
A
- intro
- macrolides
- fluorquinolones
- cephalosporins
- syngerisitc antibiotics
- negatives of antibiotics
- phages as antimicrobials
- conclusion
5
Q
antibiotic resistance
A
- intro
- breakpoints
- bacterial resistance in hospitals
- drug inactivation and iteration
- alteration in target site
- efflux pumps
- decrease in permeability
- transmission: vertical/ horizontal
- conclusion
6
Q
genetic and physiological adaptations of bacteri
A
- antibiotic resistance
- persisters
- biofilms and polymicorbial infection
- microbial seas- SAR11
- antimicrobials: bacteriocins
- evasion of host defences
7
Q
control strategiesof bacterial pathogens
A
- chemoprophylaxis- vaccines and fluoride
- education
- predicting disease- cholera
- new vaccine delivery- e.g. plague vaccines delivered through tomato capsules
- rapid
- rapid detection of pathogens- bioterrorims- using correct antibiotics
- reduced synergistic antibiotics
- conlcusion
8
Q
biofilms
A
- intro- describe
- syngergistic
- antibiotic resistance
- evasion f host defences
- prone to growing on hospital equipment
- expensive
- polmicorbial infections
- quorum sensing
9
Q
mechanism of profession phagocytes
A
- intro
- innate
- adaptive
- evasion
- repressing autophagy
10
Q
cause of host damage during infectious disease
A
-intro
-portals of entry
-establishment
-evasion of host defences
-damage
-host dependent
-virulence factors
candida
