innate vs adaptive immune system

Question 1

cells of the innate immune system e.g.

Answer 1

mast, dendritic, neutrophil, macrophage

Question 2

cells of the adaptive immune system e.g.

Answer 2

T cells and B ells

Question 3

the adaptive immune system responds to

Answer 3

antigens on the surface of the pathogen

Question 4

the innate immune system responses to

Answer 4

PAMPS on the outside of the pathogens

Question 5

PAMPS

Answer 5

pathogen associated molecular pattern - shown by viruses and bacteria

Question 6

examples of PAMPS

Answer 6

liposaccharides, lipoproteins, lipotechoich acid and peptidoglycan

Question 7

MAMP

Answer 7

more general term: microorganism associated molecular pattern= can be pathogenic or non-pathogenic

Question 8

innate immune cells have

Answer 8

PRRs which recognise pamps

Question 9

PRRs

Answer 9

pattern recognition receptors

Question 10

three types of PRRs

Answer 10

1) extracellular - in the walls of the innate cell
2) intracellular
3) secreted

Question 11

extracellular PRRs

Answer 11

are found on the outside of immune cells–> can cause engulfment or signal to the nucleus to produce cytokines

Question 12

example of extracellular PRRS

Answer 12

Toll-like receptor

Question 13

intracellular PRRs

Answer 13

found on the inside of immune cells and response to pathogens that have gained access to the cell. triggers the nucleus to produce cytokines

Question 14

example of an intracellular PRR

Answer 14

NOD receptor

Question 15

secreted PRRS

Answer 15

secreted by immune and liver cells. Complementary receptors which induce complement cascadr

Question 16

PRRs trigger innate immune responses(6)

Answer 16

• cause opsonisation
• activate complement
• phagocytose
• cytokines
• pro inflammatory
• signal apoptosis