definitions Flashcards

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1
Q

HCAI

A

infections patients get whilst receiving care in a healthcare facility

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2
Q

microbiota

A

the microorganism that typically inhabit an environment

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3
Q

microbiome

A

all the organisms, their genomes and environmental interactions in a defined environment

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4
Q

dysbiosis

A

microbial imbalances, on or within the body

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5
Q

disease

A

conditions which impair normal function of tissue

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6
Q

infection

A

invasion and colonisation of microorganisms on on within host

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7
Q

virulence

A

a continous variable, which means the amount of damage and disease that manifests

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8
Q

pathogenicity

A

a discontinuous viable, which i a microbial variable that can one be expressed in a susceptible host

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9
Q

true pathogen

A

if on/within host, it will always cause disease

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10
Q

opportunistic pathogen

A

potentially infectious agents that rarely cause disease in individuals with healthy immune systems

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11
Q

median infective does

A

the amount of pathogenic agents needed to produce demonstrable disease in 50% of the test subject

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12
Q

median lethal dose

A

the amount of pathogenic agent needed to kill 50% of the test subjects

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13
Q

morbidity rate

A

incidence of a disease across a population or geographic location per year

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14
Q

epidemiology

A

the effect of a pathogen on population where and when disease occurs
or
study and analysis of the patterns, causes, and effects of health and disease conditions in defined populations.

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15
Q

incidence

A

the number of new cases of a disease in a given area or population

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16
Q

prevalence

A

the total number of new and already existing cases

17
Q

endogenous

A

bacteria that naturally resides in a closed system

18
Q

exogenous bacteria

A

microorganisms introduced to closed biological systems from the external world- can be benign or pathogenic

19
Q

serogroup

A

microorganisms, viruses or cells which ar classified based on their cell surface antigens

20
Q

emerging infections

A

infections which are rapidly increasing in incidence or geographic range

21
Q

persistance

A

the ability of a bacteria to remain viable in a host cell for a prolonged period of time

22
Q

bacterial persisters

A

cells that represent a subset of antibiotic tolerance- slow growing or growth arrested bacterial cells that have a decreased susceptibility killing by bactericidal antibiotics in an otherwise susceptible pop.

23
Q

antibiotic resistance

A

ability of a pop of bacteria to grow in the presence of antibiotics dude to genetic modification

24
Q

bioterrorism

A

the deliberate dispersal of an infectious agent to kill or incapacity man/ and or to destroy live stock, crops and disrupt food chains

25
Q

pathogenicity island

A

a series of contiguous genes in a pathogenic microorganism including one or more that determines virulence, acquired by horizontal gene transfer.