fungal diseases Flashcards

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1
Q

Aspergillosis

A

A. fumigates, A.flavus

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2
Q

most aspergillum species do

A

not cause disease

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3
Q

route of infection for Aspergillosis

A

inhalation of spore

-‘sick building syndrome’

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4
Q

aspergillosis can range from

A

an allergy to disseminated aspergillosis

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5
Q

disseminated Aspergillosis

A

60-90% mortality

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6
Q

most dangerous diseases caused by aspergillosis are due to

A

opportunistic pathogens- immunosuppressed patients

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7
Q

cryptococcosis causative agents

A

cryptococcus neofromans and cryptoccus gattiic

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8
Q

route of infection for cryptococcosis

A

inhalation, sexual cycle produces small spores

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9
Q

what disease can Cryptoccosis cause

A

Pulmonary cryptococcosis and meningitis

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10
Q

pulmonary cryptococcosis

A

asymptomatic and chronic- can become intracellular pathogen and persist

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11
Q

cryptococcosis meningitis

A

can occur in normal individuals, but especially in AIDs patients. 30% mortality

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12
Q

cryptococcis is an

A

opportunistic/ primary pathogen

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13
Q

pneumocystis

A

caused by Pneumocystis jirovecii

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14
Q

diseases caused by Pneumocystis

A

pneumonia- dry cough/ shortness of breath

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15
Q

pneumocystis more common in

A

immunocompromised patients

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16
Q

mortality of Pneumocystis

A

5-40%

17
Q

route of infection for pneumocystis

A

inhalation

18
Q

Pneumocystis jirovecii

A

non cultural in vitro

19
Q

genome sequence of Pneumocystis

A

lacks genes for amino acid biosynthesis- scavenges amino acids from the host