Vascular Disease

Question 1

what does intrinsic activation of the coagulation cascade involve?

Answer 1

activation of factor XII

Question 2

what does prothrombin time (PT) measure?

Answer 2

the time intrinsic activation of the coagulation cascade takes

Question 3

what is the more common mechanism for activating the coagulation cascade?

Answer 3

extrinsic activation

Question 4

what starts the extrinsic activation of the coagulation cascade?

Answer 4

tissue factor

Question 5

what is the end point of the coagulation cascade?

Answer 5

prothrombin to thrombin

thrombin converting fibrinogen to fibrin

Question 6

what three factors favour the process of thrombosis?

Answer 6

endothelial injury
turbulent blood flow
hypercoagulable blood

Question 7

what is an embolism?

Answer 7

a thrombus that has travelled through blood vessels and has gotten stuck

Question 8

what is ischaemia?

Answer 8

insufficient blood supply to an area

Question 9

what is infarction?

Answer 9

death of a tissue as a result of ischaemia

Question 10

name five types of embolism that are not blood clots

Answer 10

air 
amniotic fluid 
fat 
tumour 
septic