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Y1 Principles > Autonomic Nervous System > Flashcards

Autonomic Nervous System Flashcards

1
Q

what are the two main divisions of the nervous system?

A

central nervous system, (CNS)

peripheral nervous system (PNS)

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2
Q

where does an efferent signal travel?

A

away from the CNS

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3
Q

where does an afferent signal travel?

A

towards the CNS

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4
Q

what transmitter is found in sympathetic preganglionic neurones?

A

acetylcholine

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5
Q

what transmitter is found in parasympathetic preganglionic neurones?

A

acetylcholine

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6
Q

what receptors does acetylcholine act via?

A

excitatory nicotinic cholinoceptors

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7
Q

what transmitter is found in sympathetic postganglionic neurones?

A

noradrenaline

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8
Q

what transmitter is found in parasympathetic postganglionic neurones?

A

acetylcholine

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9
Q

what is the endogenous agonist of cholinoceptors?

A

acetylcholine

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10
Q

what are the two types of cholinoceptors?

A

nicotinic

muscarinic

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11
Q

where are nicotinic ACH receptors located?

A

the ganglia

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12
Q

what are nicotinic ACH receptors?

A

ligand gated ion channels

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13
Q

where are muscarinic ACH receptors found?

A

effector cells

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14
Q

what are muscarinic ACH receptors?

A

G protein coupled receptors

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15
Q

what are the endogenous agonists of the adrenoceptors?

A

noradrenaline

adrenaline

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16
Q

what type of receptors are all adrenoceptors?

A

GPCRs

17
Q

what are the five types of adrenoceptors?

A 
a1
a2
b1
b2
b3
18
Q

what do G proteins consist of?

A

three subunits - alpha beta and gamma

a guanine nucleotide binding site in the alpha subunit

19
Q

what activates a G protein?

A

agonists binding to the GPCR

20
Q

what is found in the binding site of a G protein in the inactive state?

A

GDP

21
Q

what is found in the binding site of a G protein in the active state?

A

GTP

22
Q

what happens to a G protein in the active state?

A

beta/gamma subunits separate from the alpha subunit

Y1 Principles (38 decks)

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