Public Health Flashcards
what is at the top of the evidence pyramid?
systematic reviews
what are the four stages of a clinical trial?
clinical pharmacology
initial clinical assessment
rigorous testing
post marketing surveillance
name four factors that can influence the outcome of a clinical trial
severity of illness
current treatments
past medical history
age
name two pieces of inclusion criteria for a patient in a trial
they are likely to benefit from the treatment
they are unlikely to be harmed by the treatment
name two pieces of exclusion criteria for a patient in a trial
they/the doctor has a preference for the intervention or control
unlikely to adhere to the treatment
how can patients be lost during a clinical trial?
emigration
death
voluntary withdrawal
what is the rule of thumb for patient loss in a trial?
less than 20% loss, with similar losses for both groups
