UC vs Crohn's Flashcards
In which is bloody diarrhoea more common?
Ulcerative colitis
Where is there abdominal pain in UC?
LLQ
Tenesmus
In which condition is weight loss more prominent?
Crohn’s disease
What extra-intestinal condition is associated with UC?
Primary sclerosing cholangitis
Which extra-intestinal conditon is associated with Crohn’s?
Gallstones (reduced bile acid absorption)
What are the possible complications of Crohn’s?
Obstruction
Fistula
Colorectal cancer
In which condition is colorectal cancer more common?
UC
Where does the disease affect in Crohns?
Anywhere from mouth to anus
Where does the disease affect in UC?
Inflammation starts at rectum and never spreads beyond ileocaecal valve
How does inflammation spread in Crohn’s?
Inflammation in all layers from mucosa to serosa
How does inflammation spread in UC?
No inflammation beyond submucosa
What would you see on histology in someone with Crohn’s?
increased goblet cells
granulomas
What would you see on histology of UC?
Crypt abscesses
depletion of goblet cells and mucin from gland epithelium
What would you see on endoscopy of crohn’s?
Deep ulcers, skip lesions - ‘cobble-stone’ appearance
What would you see on endoscopy of UC?
pseudopolyps
