Cholangiocarcinoma Flashcards
What is cholangiocarcinoma?
Cancer that originates in the bile ducts
What type of cancer are the majority of cholangiocarcinoma’s?
Adenocarcinomas
Which region is most commonly affected by cholangiocarcinoma?
Perihilar region
What are the main risk factors of cholangiocarcinoma?
Primary sclerosing cholangitis
Liver flukes
How does cholangiocarcinoma present?
Obstructive jaundice
Courvoisier’s
Hepatomegaly
What how does obstructive jaundice present?
Pale stool
Dark urine
Generalised itching
What is Courvoisier’s sign?
Palpable gallbladder
Jaundice
What is the management of cholangiocarcinoma?
ERCP- Diagnostic and management
Curative surgery
Chemo and radio
How is cholangiocarcinoma diagnosed?
CT/MRI
Histology from biopsy
How is cholangiocarcinoma staged?
CT of thorax, abdomen and pelvis
What might be raised with cholangiocarcinoma?
CA19-9
What is the function of ERCP?
Put a stent in and relive obstruction
What is used to assess the obstruction in cholangiocarcinoma
MRCP
What is used in the palliative treatment of cholangiocarcinoma?
ERCP-Stent to relieve obstruction
Surgery to improve symptoms
Palliative chemo and radio
