Liver function test results

Question 1

What would suggest an obstructive cause due to pancreatic cancer (obstruction of the biliary tree?

Answer 1

Raised Bilirubin, ALP,
ALT, Gamma-GT
(bigger raise in ALP and GGT than ALT)

Question 2

What would suggest primary sclerosing cholangitis?

Answer 2

Raised Bilirubin and markedly rasied ALP in the presence of P-ANCA positibe or UC and jaundice symptoms but no pain

Question 3

What would suggest Gilbert’s syndrome?

Answer 3

An isolated raised bilirubin in response to pysiological stress (viral illness)

Question 4

What would suggest pancreatic cancer?

Answer 4

Raised ALP and bilirubin
slight raise in gamma GT
painless, non-specific signs (itch and weight loss)

Question 5

What would indicate alcoholic liver disease?

Answer 5

AST:ALT is normally > 2,
Gamma GT elevated
History of alcohol abuse