Translation Flashcards
Translation
mRNA is decoded to build a protein that contains a specific series of amino acids
Codons
Groups of three RNA nucleotides that are the instructions for building a polypeptide in the mRNA, read in groups of three
Start codon
AUG, Signals the start of protein construction
Stop codons
Codons that do not specify amino acids and tell the cell when the polypeptide is complete.
UAA, UAG, and UGA
How many codons are there for amino acids and as start and stop codons
64 codons in total, 61 for amino acids
Transfer RNAs
Molecular “bridges” that connect mRNA codons to the amino acids they encode
tRNA
molecular bridges that connect mRNA codons to the amino acids they encode
One end has an anticodon
Another end carries the amino acid specified by codons
anticodon
One end of each tRNA contains an anticodon that binds to specific mRNA codons.
Ribosomes
Wher polypeptides (proteins) are built. Made up of protein and rRNA (ribosomal RNA)
Ribosome structure
Has two subunits (one large and small) that come together around an mRNA
Provides slots called A,P, and E sites where tRNAs can find their matching codons on the mRNA template
Translation
Initiation, Elongation and Termination
Initiation
Ribosome gets together with the mRNA and the first tRNA so translation can begin
Elongation
Amino acids are brough to the ribosome by the tRNAs and linked together to form a chain
Termination
The finished polypeptide is released to go and do its job in the cell
Termination happens when a stop codon in the mRNA enters the A site
Release factors
Proteins that recognize stop codons