Chapter 17 Flashcards

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1
Q

Translation

A

Sequence of mRNA bases are converted to an amino acid sequence

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2
Q

Codons

A

Groups of three RNA nucleotides that the instructions for building a polypeptide

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3
Q

How many codons are there?

A

61 to specify amino acids and three codons as start and stop signals

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4
Q

Start codon

A

AUG codon that signals the start of protein construction

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5
Q

Stop codons

A

UAA, UAG, and UGA that tell the cell when a polypeptide is complete

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6
Q

Genetic code

A

Collection of codon-amino acid relationships

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7
Q

Two types of molecules with key roles in translation

A

tRNAs and ribosomes

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8
Q

tRNA

A

Molecular bridges that connect mRNA codons to the amino acids they encode

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9
Q

Anticodon

A

Sequence of three codons at the end of each tRNA that binds to specific mRNA codons

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10
Q

Template strand

A

strand read by RNA polymerase in transcription

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10
Q

coding strand

A

strand of DNA that is not transcribed during synthesis of RNA

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11
Q

Transcription in Eukaryotic differences

A
  1. Three RNA polymerase: RNA polymerase 1, 2 and 3
  2. Larger, more diverse promoters, including TATA box
  3. General transcription factors recognize promoters rather than sigma proteins.
  4. At termination a poly(A) signal is transcribed rather than a hair pin
  5. Transcription occurs in the nucleus and translation occurs in the cytoplasm.
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12
Q

TATA box

A

short DNA sequence in many eukaryotic located about 30 pairs upward of the transcription start site. Important for assembling general transcription factors and RNA polymerase at the core enzyme.

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13
Q

General transcription factors

A

Group of proteins that assemble on promoters and help RNA polymerase initiate transcription

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14
Q

Termination of transcription for eukaryotic protein-coding genes

A

A DNA sequence near the end of each gene called poly(A) signal, is transcribed.

The RNA downstream of the poly(A) signal sequence is cut by an enzyme as the polymerase continues to transcribe the DNA template.

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15
Q

Where does transcription occur in eukaryotes?

A

Transcription occurs in the nucleus and translation occurs by using ribosomes located in the cytoplasm..

16
Q

Primary transcripts

A

Newly transcribed RNA molecule that has not been processed to a mature RNA

17
Q

pre-mRNA

A

The primary transcript of protein-coding genes

18
Q

RNA processing

A

Changes that a primary

19
Q
A