thyroid disorders Flashcards
1
Q
therapeutic action Thyroxine
A
hypothyroidism
2
Q
mechanism of action Thyroxine
A
Thyroxine is metabolised yo T3, hereby replacing the decreased volume of endogenous thyroid hormones
3
Q
adverse effects Thyroxine
A
weight loss
insomnia
elevated temperature
4
Q
contraindications Thyroxine
A
hyperthyroidism
diabetes type II
5
Q
drug interaction Thyroxine
A
Warfarin
6
Q
therapeutic action Carbimazole
A
Hyperthyroidism
7
Q
mechanism of action Carbimazole
A
synthesis impediment of thyroid hormones;
the organic binding of I2 gets inhibited by higher concentrations in the thyroid gland, causing an anti-thyroid effect.
8
Q
adverse effects Carbimazole
A
nausea
vomiting
rash
9
Q
contraindications Carbimazole
A
pregnancy
10
Q
drug interaction Carbimazole
A
Warfarin
